Results 231 to 240 of about 217,614 (319)

Changes in the Interaction Properties of Antibodies with Fc Receptors upon Binding to Target Antigens. [PDF]

open access: yesBiosensors (Basel)
Grevtsev AS   +9 more
europepmc   +1 more source

Research Progress on Wavelength Modulation Technologies of Crystalline Raman Lasers

open access: yesAdvanced Photonics Research, Volume 7, Issue 1, January 2026.
This article summarizes the research progress in wavelength modulation technologies for crystalline Raman lasers. It systematically classifies and examines four key types: tunable, switchable, dual‐wavelength, and multi‐wavelength crystalline Raman lasers.
Xiaobo Mi   +4 more
wiley   +1 more source

HERV‐K TM Subunit Elicits CD8+ T Cell Anergy and Tumor Immune Evasion via Targeting CD3 Coreceptor ε in AML and PDAC

open access: yesAdvanced Science, Volume 13, Issue 1, 5 January 2026.
Novel viral immune checkpoint K‐TM subunit is aberrantly expressed in CD8+ T cells and enriched in sera of cancer patients, inducing CD8+ T cell anergy and eliciting potent tumor immune escape in mouse model. Mechanistically, K‐TM directly targets and induces the phosphorylation of CD3ε receptor.
Mengyuan Li   +13 more
wiley   +1 more source

Aptamer Engineering: Strategies for Discovering Functional Nucleic Acids for Next‐Generation Diagnostics and Biosensing

open access: yesAdvanced Science, Volume 13, Issue 2, 9 January 2026.
The advent of aptamers has highlighted their potential as alternatives to antibodies, overcoming limitations of structural instability and production cost. However, conventional approaches such as SELEX remain slow and labor‐intensive. This review examines recent advances in aptamer engineering, emphasizing in vitro and AI‐driven in silico strategies ...
John V. L. Nguyen   +5 more
wiley   +1 more source

X-ray phase measurements by time-energy correlated photon pairs. [PDF]

open access: yesSci Adv
Klein Y   +9 more
europepmc   +1 more source

Next‐generation Alzheimer's therapeutics: target assessment and enablement at the Indiana University School of Medicine–Purdue University TREAT‐AD Center

open access: yesAlzheimer's &Dementia, Volume 22, Issue 1, January 2026.
Abstract The incidence of Alzheimer's disease (AD) continues to increase, despite decades of effort to develop disease‐modifying therapies. In response, the National Institute on Aging (NIA) established the TaRget Enablement to Accelerate Therapy Development for Alzheimer's Disease (TREAT‐AD) centers to address the gap between basic research and ...
Timothy I. Richardson   +8 more
wiley   +1 more source

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