Results 251 to 260 of about 236,225 (308)

Study of Thyroid Function Indices (T3, T4, a-Tpo, Tg, a-Tg) During Hepatitis B in Khoy City, İran, Before Alpha-Interferon Therapy

, 2019
Hajer Jafarpour, Kaveh Azimzadeh
openalex   +1 more source

Macrophage TRIM21 Inhibition Ameliorates Murine Acute Pancreatitis via PHB2‐Mediated Mitochondrial Stabilization

Advanced Science, EarlyView.
Macrophage‐derived TRIM21 drives the progression of AP via ubiquitin‐proteasome‐mediated degradation of PHB2, leading to impaired PHB2‐mediated mitophagy. Therefore, accumulation of cytosolic mtDNA hyperactivates the cGAS‐STING signaling axis, thereby amplifying inflammatory cascades.
Yansong Xu, Yuansong Sun, Xin Zhou, Kai Song, Chunlin Yin, Zhaohua Wang, Fei Xie, He Li   +7 more
wiley   +1 more source

A pH-Responsive Poly Beta-Amino Ester Nanoparticulate Thermo-Responsive PEG-PCL-PEG Hydrogel Dispersed System for the Delivery of Interferon Alpha to the Ocular Surface. [PDF]

Pharmaceutics
Abdalla Y, du Toit LC, Ubanako P, Choonara YE.   +3 more
europepmc   +1 more source

Interferon-alpha immunotherapy of melanoma: signal transduction, gene transcription, and the role of suppressor of cytokine signaling proteins in immune cells

, 2007
Jason M. Zimmerer
openalex   +1 more source

Biomimetic Organic Nanozyme as Tumor Vaccines for Targeted Suppression of Ammonia‐Induced T Lymphocyte Death to Augment Breast Cancer Immunotherapy

Advanced Science, EarlyView.
The organic nanozyme IR‐IHpd, which has NIR‐PDT and POD‐like activity, is designed for continuous ROS generation. It is co‐encapsulated with CB‐839 and coated with DC membranes to simultaneously target tumors and T cells. Under NIR irradiation, immunogenic cell death is activated. Concurrently, CB‐839 suppresses ammonia‐induced T lymphocyte death (AITD)
Meng Suo, Deyi Yang, Mingpu Yang, Jue Wang, Dingfeng Zhang, Daoming Zhu, Qingyong Xu, Yanni Song   +7 more
wiley   +1 more source

Tumor Integrin-Targeted Glucose Oxidase Enzyme Promotes ROS-Mediated Cell Death that Combines with Interferon Alpha Therapy for Tumor Control. [PDF]

Mol Cancer Ther
Stinson JA, Sheen A, Lax BM, Yang GN, Duhamel L, Santollani L, Fink E, Palmeri JR, Wittrup KD.   +8 more
europepmc   +1 more source

Systems Biology in 874 Patients with Primary Sjogren's Syndrome Indicates the Predominant Role of Interferon Alpha Compared to Interferon Gamma, Its Association with Systemic Complications, and a New Aspect of the Genetic Contribution of HLA

, 2019
Pierre Bost, Xavier Mariette, Vincent Bondet, Alba Llibre, Céline Posseme, Bruno Charbit, Christian W. Thorball, Roland Jonsson, Chris Lessard, Renaud Felten, Fai Ng, Katherine Silvis, Lucienne Chatenoud, Hélène Dumortier, Jacques Fellay, Karl A. Brostadt, Silke Appel, Jessica Tarn, Lluís Quintana‐Murci, Michael Minguenau, Nicolás Meyer, Darragh Duffy, Benno Schwikowski, Jacques‐Eric Gottenberg   +23 more
openalex   +1 more source

Impact of Non‐Alcoholic Fatty Liver Disease on the HBsAg Loss of Patients With Chronic Hepatitis B Treated in Pegylated Interferon Alpha [PDF]

Chujing Li, Lihua Lin, Pei Zhou, Haiyi Cai, Songlian Liu, Xiaohong Chen, Aiqi Lu, Bo Li, Yaping Wang, Chuanghua Luo, Jianping Li, Guan Yu-juan, Zhiwei Xie   +12 more
openalex   +1 more source

Inferring Gene Regulatory Networks From Single‐Cell RNA Sequencing Data by Dual‐Role Graph Contrastive Learning

Advanced Science, EarlyView.
RegGAIN is a novel and powerful deep learning framework for inferring gene regulatory networks (GRNs) from single‐cell RNA sequencing data. By integrating self‐supervised contrastive learning with dual‐role gene representations, it consistently outperforms existing methods in both accuracy and robustness.
Qiyuan Guan, Jiating Yu, Jieyi Pan, Fan Yuan, Jiadong Ji, Rusong Zhao, Zhi‐Ping Liu, Bingqiang Liu, Ling‐Yun Wu, Duanchen Sun   +9 more
wiley   +1 more source

EFFECTS OF TREATMENT WITH TEMSIROLIMUS VERSUS INTERFERON ALPHA ON SURVIVAL OF PATIENTS WITH METASTATIC RENAL CELL CARCINOMA - SINGLE-CENTER REAL-WORLD EXPERIENCE. [PDF]

Acta Clin Croat
Levakov I, Vojinov S, Maletin M, Jeremić D, Popov M, Levakov O, Grbić D.   +6 more
europepmc   +1 more source