Results 191 to 200 of about 527,002 (316)

Exhausted natural killer cells in adult IgA vasculitis. [PDF]

open access: yesArthritis Res Ther
Bajželj M   +10 more
europepmc   +1 more source

Lactylation‐Driven NUPR1 Promotes Immunosuppression of Tumor‐Infiltrating Macrophages in Hepatocellular Carcinoma

open access: yesAdvanced Science, EarlyView.
Cai et al. report that tumor‐derived lactate induces NUPR1 expression via H3K18 lactylation, which can promote the pro‐tumor M2 macrophage polarization through ERK and JNK signaling pathways. Treatment with NUPR1 selective inhibitor sensitizes synergizes with anti‐PD‐1 therapy in murine preclinical models.
Jialiang Cai   +12 more
wiley   +1 more source

The first trimester human placenta responds to Zika virus infection inducing an interferon (IFN) and antiviral interferon stimulated gene (ISG) response. [PDF]

open access: yesVirol J
Van der Hoek KH   +6 more
europepmc   +1 more source

Comparative Studies on the Production and Assay of Interferon

open access: bronze, 1964
George E. Gifford   +2 more
openalex   +1 more source

Targeting COPA to Enhance Erdafitinib Sensitivity in FGFR‐Altered Bladder Cancer

open access: yesAdvanced Science, EarlyView.
Coatomer protein complex subunit α facilitates the transport of the cargo protein LRPPRC across the Golgi complex and enhances its stability, thereby increasing LRPPRC expression; LRPPRC promotes the stability of ID3 mRNA in an m6A‐dependent manner, thereby decreasing the transcriptional activity of p16 and p21, which leads to increased erdafitinib ...
Huayuan Zhao   +10 more
wiley   +1 more source

Host transcriptome response to Mycoplasma bovis and bovine viral diarrhea virus in bovine tissues. [PDF]

open access: yesBMC Genomics
Goldkamp AK   +5 more
europepmc   +1 more source

Verteporfin‐Mediated In Situ Nanovaccine Based on Local Conventional‐Dose Hypofractionated Radiotherapy Enhances Antitumor and Immunomodulatory Effect

open access: yesAdvanced Science, EarlyView.
Here gelatinase‐responsive methoxypolyethyleneglycol–PVGLIG–polycaprolactone (mPEG–PVGLIG–PCL) nanoparticles’ loading verteporfin (N@VP) is developed, enhancing radiotherapy via X‐ray‐triggered singlet oxygen generation. Combined with 2 Gy (gray, a radiation dose unit) irradiation, N@VP achieves antitumor efficacy comparable to 8 Gy, and also promotes ...
Zhifan Zhang   +16 more
wiley   +1 more source

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