Results 261 to 270 of about 1,191,146 (396)

Plaque Development and Induction of Interferon Synthesis by RMC Poliovirus [PDF]

, 1965
Terry C. Johnson, Leroy C. McLaren
openalex   +1 more source

Intestinal Epithelial‐Derived USP13 Alleviates Colonic Inflammation by Suppressing GRP78‐mediated Endoplasmic Reticulum Stress

Advanced Science, EarlyView.
USP13 deficiency in intestinal epithelial cells aggravates DSS‐induced colitis by enhancing ER stress and apoptosis. USP13 interacts with GRP78 and reduces its K63‐linked ubiquitination to alleviate epithelial injury. Restoring USP13 expression or targeting the USP13‐GRP78 axis may represent a promising strategy for treating inflammatory bowel disease ...
Chenchen Qian, Chenghong Hu, Yong Xu, Wentao Xu, Zhe Wang, Wan Gan, Weiyang Tang, Lijiang Huang, Aleksandr V. Samorodov, Yi Wang   +9 more
wiley   +1 more source

INHIBITION OF INTERFERON PRODUCTION BY CHLOROQUINE DIPHOSPHATE

, 1968
S. Kohno, Masayoshi Kohase, Masaru Suganuma   +2 more
openalex   +2 more sources

Relation of interferon synthesis to abortive replication of Newcastle disease virus in L cells [PDF]

, 1968
Juliuss . Youngner, Anne W. Scott
openalex   +1 more source

NSP7 Molecular Degrader Attenuates Coronaviral Infection Through the β‐TrCP1/FBXO5 Axis

Advanced Science, EarlyView.
Host E3 ligase FBXO5 as a key regulator that promotes K48‐linked ubiquitination and proteasomal degradation of SARS‐CoV‐2 NSP7, thereby suppressing viral replication. NSP7 ubiquitination is co‐regulated by β‐TrCP1 and TAF1. Small molecule BC24877 disrupts β‐TrCP1‐mediated degradation of FBXO5, stabilizing FBXO5 and enhancing NSP7 clearance ...
Yao Tong, Travis B. Lear, Ferhan Tuncer, John J. Villandre, Áine N. Boudreau, Bo Lin, Irene Alfaras, Jason R. Kennerdell, Daniel P. Camarco, Mads B. Larsen, Yun Hua, Yanwen Chen, Meigin E. Chandler, Ricardo Pineda, Simon M. Barratt‐Boyes, John W. Evankovich, Toren Finkel, Yuan Liu, Bill B. Chen   +18 more
wiley   +1 more source

Highlights from MPN Asia 2025: Advances in Molecular Pathogenesis and Therapeutic Strategies in Myeloproliferative Neoplasms. [PDF]

Curr Hematol Malig Rep
Bose P, Xiao Z, Hasselbalch HC, Prchal JT, Duan M, Yacoub A, Rampal R, Kiladjian JJ, Hobbs GS, Tashi T, Shimoda K, Kirito K, Gill H, Hou HA, Lee SE, Huang J, Li B, Qin A, Yu LH, Mascarenhas JO, Mesa RA.   +20 more
europepmc   +1 more source

Hepatitis C Virus Resistance to Direct-Acting Antiviral Drugs in Interferon-Free Regimens.

Gastroenterology, 2016
J. Pawlotsky
semanticscholar   +1 more source

Production of Interferon in Mice: Effect of Altered Gaseous Environments [PDF]

, 1968
Kun-Yen Huang, Francis B. Gordon
openalex   +1 more source

Type I Interferon Signaling Augments Autoimmunity in Neuromyelitis Optica Spectrum Disorder

Advanced Science, EarlyView.
The cGAS‐STING innate immune pathway is excessively activated both in peripheral monocytes and CNS microglia in patients with NMOSD, leading to an overproduction of IFN‐I. IFN‐I subsequently acts on AQP4‐specific autoreactive T cells. Blocking this pathway may offer novel therapeutic options for individuals with NMOSD.
Tian‐Xiang Zhang, Xiaoxiao Yang, Xue Gao, Xiaoshan Du, Xuegan Lian, Naiyuan Shao, Ye Liu, Zhenning Huang, Dongmei Jia, Alexander Y. L. Lau, Zhiguo Li, Zaal Kokaia, Fu‐Dong Shi, Chao Zhang   +13 more
wiley   +1 more source

Determinants of functional cure in interferon-treated chronic hepatitis B: a retrospective cohort analysis of HBsAg dynamics and clinical predictors. [PDF]

Front Cell Infect Microbiol
Zhou D, Jia J, Zhao F, Liu J, Zhang Z, Cao Z.   +5 more
europepmc   +1 more source