Results 281 to 290 of about 1,191,146 (396)

The Role of Interferon in Persistent Infection with Foot-and-Mouth Disease Virus

, 1963
Lennart Philipson, Z. Dinter
openalex   +1 more source

Human Schlafen 14 Cleavage of Short Double‐Stranded RNAs Underpins its Antiviral Activity

Advanced Science, EarlyView.
SLFN14 is associated with human diseases. SLFN14 is found to cleave RNAs containing short duplexes. The cryo‐EM structures of SLFN14 and SLFN14‐hairpin RNA complex reveal that SLFN14 assembles into a ring‐like dimer; two RNase domains form an RNA‐binding groove accommodating a hairpin RNA.
Mengyun Li, Dapeng Sun, Wei Hao, Hua Fu, Yueli Zhang, Zhijian Li, Bo Qin, Yumei Wang, Sheng Cui   +8 more
wiley   +1 more source

Quantitative Assay of Interferon by the Immunofluorescent Cell-counting Technique

, 1969
Edmund H. Kozikowski, Nicholas Hahon
openalex   +1 more source

Post‐Translational Modified Neoantigens in Autoimmune Diseases: Challenges of Immune Tolerance

Advanced Science, EarlyView.
Autoimmune diseases have a high incidence and disability rate. The pathogenesis of autoimmune diseases involves the interaction among genetic factors, environmental factors, and immune disorders. The post‐translational modified neoantigens are the key nodal of these three factors. And these post‐translational modified neoantigens, after being presented
Yue Zhai, Kefei Wu, Qi Lin, Zhenzhen Cao, Yankun Jia, Ping Zhu   +5 more
wiley   +1 more source

Marked improvement of oral manifestations in systemic lupus erythematosus after therapy with IFNAR1 blocking antibody (anifrolumab): A case report. [PDF]

Int J Surg Case Rep
Schiepek T, Grün P, Turhani F, Grün AS, Holzhauer S, Turhani D.   +5 more
europepmc   +1 more source

FLASH Irradiation Modulates Immune Responses and Accelerates Lung Recovery: A Single‐Cell Perspective

Advanced Science, EarlyView.
Single‐cell RNA sequencing reveals distinct immune responses to FLASH versus conventional dose rate irradiation in early radiation‐induced lung injury. FLASH irradiation reduces Ccrl2⁺ neutrophil infiltration, activates CD4⁺ CD40L⁺ Th cells, restrains pro‐inflammatory Mefv⁺ monocytes, and enhances epithelial repair via TGF‐β signaling, underscoring its
Hao Lu, Menghua Li, Cheng Quan, Caihui Li, Dawei Li, Zhihui Li, Jing Xu, Lihui Zhang, Qixiang Liu, Guofu Dong, Changzhen Wang   +10 more
wiley   +1 more source

Extracellular BAG3 is elevated in early diffuse systemic sclerosis. [PDF]

Mil Med Res
Freedman P, De Marco M, Rosati A, Marzullo L, Del Papa N, Turco MC, O'Reilly S.   +6 more
europepmc   +1 more source

Type I interferon in rheumatic diseases

Nature Reviews Rheumatology, 2018
T. W. Muskardin, T. Niewold
semanticscholar   +1 more source

Cardiovascular Disease Meets Cancer: Exploring the Epidemiology in China and Homotherapy Targeting Intersectional Mechanisms

Advanced Science, EarlyView.
Cardiovascular disease (CVD) and cancer are leading causes of death worldwide, with overlapping risk factors and pathophysiological mechanisms. This review explores shared pathways, including metabolic dysregulation, chronic inflammation, and gut microbiome alterations, highlighting dual‐benefit strategies such as lifestyle modifications and repurposed
Shihan Xiang, Yujie Shan, Shihong Xu, Jing Wang, Meng Luo, Jiaojiao Zhou, Qishan Chen   +6 more
wiley   +1 more source

Targeting interferon responses in juvenile dermatomyositis: Siglec-1 as an in vitro biomarker for JAK inhibitor efficacy. [PDF]

Rheumatology (Oxford)
Veldkamp SR, Reugebrink M, Evers SW, Moreau TRJ, Bondet V, Armbrust W, van den Berg JM, Hissink Muller PCE, Kamphuis S, Schatorjé E, Delemarre EM, van der Kooi AJ, Bader-Meunier B, Duffy D, Rodero MP, Raaphorst J, van Royen-Kerkhof A, Jansen MHA, van Wijk F.   +18 more
europepmc   +1 more source