Results 31 to 40 of about 373,840 (223)

Erdheim Chester disease: a subtle quiddity; the first case reported from Nepal

open access: yesRadiology Case Reports, 2020
Erdheim-Chester disease (ECD) is a rare entity throughout the world. This is the first case reported in Nepal. ECD is a rare aggressive, non-Langerhan's histocytosis of unknown origin with classical histological features.
Pawan Singh, MBBS   +2 more
doaj   +1 more source

Safety and efficacy of REP 2139 and pegylated interferon alfa-2a for treatment-naive patients with chronic hepatitis B virus and hepatitis D virus co-infection (REP 301 and REP 301-LTF): a non-randomised, open-label, phase 2 trial.

open access: yesThe Lancet Gastroenterology and Hepatology, 2017
BACKGROUND REP 2139 clears circulating hepatitis B virus (HBV) surface antigen (HBsAg), enhancing the restoration of functional control of HBV infection by immunotherapy. We assessed the safety and efficacy of REP 2139 and pegylated interferon alfa-2a in
M. Bazinet   +13 more
semanticscholar   +1 more source

Ropeginterferon Alfa-2b administered every two weeks for patients with genotype 2 chronic hepatitis C

open access: yesJournal of the Formosan Medical Association, 2021
Background: Ropeginterferon alfa-2b is a novel mono-pegylated interferon that has only one major form as opposed to the 8 to 14 isomers of other on-market pegylated interferon products, allowing every-two-week injection with high tolerability.
Shih-Jer Hsu   +15 more
doaj   +1 more source

HBsAg Loss with Peg-interferon Alfa-2a in Hepatitis B Patients with Partial Response to Nucleos(t)ide Analog: New Switch Study

open access: yesJournal of Clinical and Translational Hepatology, 2018
Background and Aims: Hepatitis B surface antigen (HBsAg) loss is seldom achieved with nucleos(t)ide analog (NA) therapy in chronic hepatitis B patients but may be enhanced by switching to finite pegylated-interferon (Peg-IFN) alfa-2a.
P. Hu   +26 more
semanticscholar   +1 more source

Thyrotoxicosis With Pegylated Interferon Alfa-2b [PDF]

open access: yesArchives of Dermatology, 2010
Despite adequate surgery, a diagnosis of stage III melanoma carries a high risk of relapse, and hence mortality. Interferon alfa is the only treatment that has currently been shown to alter the natural history of the disease, delaying relapse-free survival, particularly in patients with micrometastatic disease.
Lowndes, SA, Asher, R, Middleton, MR
openaire   +2 more sources

Onset of Celiac Disease after Treatment of Chronic Hepatitis C with Interferon Based Triple Therapy

open access: yesCase Reports in Hepatology, 2015
Background. Patients treated with interferon (IFN) based therapies may develop exacerbation of autoimmune disease. We herein present the case of a 53-year-old female patient who developed celiac disease (CD) as a result of triple therapy (interferon ...
Amandeep Singh   +2 more
doaj   +1 more source

The expirience of IDEAL

open access: yesЖурнал инфектологии, 2014
Combination therapy with pegylated interferon-α and ribavirin is the modern standard of chronic hepatitis C treatment [1-3] in Russian Federation [4]. This particular regimen provides achieving of sustained virological response (SVR) in 42-28% of patient
E. Z. Burnevich
doaj   +1 more source

VIR-2218 (elebsiran) plus pegylated interferon-alfa-2a in participants with chronic hepatitis B virus infection: a phase 2 study.

open access: yesThe Lancet Gastroenterology and Hepatology
BACKGROUND Chronic hepatitis B virus (HBV) remains a global concern, with current treatments achieving low rates of HBsAg seroclearance. VIR-2218 (elebsiran), a small interfering RNA agent against HBV transcripts, reduces HBsAg concentrations.
M. Yuen   +14 more
semanticscholar   +1 more source

Safety and efficacy of nilotinib after 10 years of interferon

open access: yesClinical Management Issues, 2015
Here we describe a case of a woman with chronic myeloid leukemia at high risk, according to the Sokal Index. The patient started interferon alfa-2b (IFN) at standard dose obtaining a major molecular response after about four years of treatment.
Filippo Russo
doaj   +1 more source

Interferon-based therapy decreases risks of hepatocellular carcinoma and complications of cirrhosis in chronic hepatitis C patients. [PDF]

open access: yesPLoS ONE, 2013
Interferon-based therapy (IBT) has been the standard of care for hepatitis C virus (HCV) infection. However, conflicting results exist regarding the effects of IBT on risk of developing hepatocellular carcinoma (HCC) and cirrhosis-associated ...
Ching-Sheng Hsu   +6 more
doaj   +1 more source

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