Results 1 to 10 of about 190,093 (164)
Annals of Medicine, 2021 Background There are few effective therapies for coronavirus disease 2019 (COVID-19) upon the outbreak of the pandemic. To compare the effectiveness of a novel genetically engineered recombinant super-compound interferon (rSIFN-co) with traditional ...
Chuan Li, Fengming Luo, Nian Xiong
exaly +3 more sources
Interferon alpha-induced reduction in the values of myeloid-derived suppressor cells in melanoma patients [PDF]
Vojnosanitetski Pregled, 2015 Background/Aim. Interaction between tumor cells and host’s immunoregulatory cells in creation of microenvironment that supports tumor progression is the focus of numerous investigations in recent years.
Stanojević Ivan +11 more
doaj +1 more source
Use of Pegylated Interferon Alpha-2a in Cutaneous T-cell Lymphoma: A Retrospective Case Collection
Acta Dermato-Venereologica, 2023 Mycosis fungoides and Sézary syndrome are rare and largely incurable types of cutaneous T-cell lymphoma with limited therapeutic options. In 1984 Bunn et al.
Janika Gosmann +4 more
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Aspects of a Methodological Approach to Determination of Interferon Alpha Specific Activity
Биопрепараты: Профилактика, диагностика, лечение, 2020 Specific antiviral activity is one of the key indicators characterising pharmaceutical quality and pharmacological efficacy of interferon alpha products (IFN-α).
M. L. Baykova +4 more
doaj +1 more source
Anti-interferon alpha autoantibodies and their significance in COVID-19
Инфекция и иммунитет, 2022 During the last two years, treatment of patients with novel coronavirus infection COVID-19 remains an urgent health problem. Interferon proteins are known to play a significant role in antiviral immunity.
S. S. Petrikov +5 more
doaj +1 more source
Journal of Translational Medicine, 2008 Background To determine the role of interferon-alpha in controlling HIV infection we phenotypically and functionally analyzed circulating plasmacytoid dendritic cells (pDC), which are known to be the highest interferon-alpha producing cells, in 33 ...
Plebani Alessandro +10 more
doaj +1 more source
Recombinant alpha-2-interferon for hairy cell leukemia [PDF]
Blood, 1985 Twenty-two patients with hairy cell leukemia were treated with biosynthetic (recombinant) alpha-2-interferon in an open-label, single- arm efficacy study. Patients received 2 X 10(6) U/m2 recombinant alpha- 2-interferon three times weekly. Therapy was well tolerated subjectively with minimal short-term hematologic toxicity.
A D, Jacobs, R E, Champlin, D W, Golde
openaire +3 more sources
The value of interferon therapy for COVID-19 in children
Детские инфекции (Москва), 2021 The article presents a literature review, which provides data on the role of interferons in the immunopathogenesis of COVID-19 and the clinical efficacy of drugs based on recombinant interferon-alpha 2b in the treatment of children with new coronavirus ...
L. N. Mazankova +2 more
doaj +1 more source
Antiviral Activity of Interferon Alpha-2b and Taurine Combination Against SARS-CoV-2 in vitro
Антибиотики и Химиотерапия, 2022 Interferons (IFN) have antiviral activity against many viruses, including SARS-CoV-2. A combination of IFN-a2b and the antioxidant taurine is widely used in the Russian Federation, and its antiviral activity has not been studied before.
N. P. Kartashova +5 more
doaj +1 more source
Interferon impedes an early step of hepatitis delta virus infection. [PDF]
PLoS ONE, 2011 Hepatitis delta virus (HDV) infects hepatocytes, the major cell type of the liver. Infection of the liver may be either transient or chronic. The prognosis for patients with chronic HDV infection is poor, with a high risk of cirrhosis and hepatocellular ...
Ziying Han +4 more
doaj +1 more source