Results 1 to 10 of about 25,282,834 (298)
Annals of Medicine, 2021 Background There are few effective therapies for coronavirus disease 2019 (COVID-19) upon the outbreak of the pandemic. To compare the effectiveness of a novel genetically engineered recombinant super-compound interferon (rSIFN-co) with traditional ...
Nan Chen, Weimin Li, Dan Liu
exaly +3 more sources
Interferon alpha-induced reduction in the values of myeloid-derived suppressor cells in melanoma patients [PDF]
Vojnosanitetski Pregled, 2015 Background/Aim. Interaction between tumor cells and host’s immunoregulatory cells in creation of microenvironment that supports tumor progression is the focus of numerous investigations in recent years.
Stanojević Ivan +11 more
doaj +1 more source
Use of Pegylated Interferon Alpha-2a in Cutaneous T-cell Lymphoma: A Retrospective Case Collection
Acta Dermato-Venereologica, 2023 Mycosis fungoides and Sézary syndrome are rare and largely incurable types of cutaneous T-cell lymphoma with limited therapeutic options. In 1984 Bunn et al.
Janika Gosmann +4 more
doaj +1 more source
Aspects of a Methodological Approach to Determination of Interferon Alpha Specific Activity
Биопрепараты: Профилактика, диагностика, лечение, 2020 Specific antiviral activity is one of the key indicators characterising pharmaceutical quality and pharmacological efficacy of interferon alpha products (IFN-α).
M. L. Baykova +4 more
doaj +1 more source
Anti-interferon alpha autoantibodies and their significance in COVID-19
Инфекция и иммунитет, 2022 During the last two years, treatment of patients with novel coronavirus infection COVID-19 remains an urgent health problem. Interferon proteins are known to play a significant role in antiviral immunity.
S. S. Petrikov +5 more
doaj +1 more source
Journal of Translational Medicine, 2008 Background To determine the role of interferon-alpha in controlling HIV infection we phenotypically and functionally analyzed circulating plasmacytoid dendritic cells (pDC), which are known to be the highest interferon-alpha producing cells, in 33 ...
Plebani Alessandro +10 more
doaj +1 more source
Recombinant alpha-2-interferon for hairy cell leukemia [PDF]
Blood, 1985 Twenty-two patients with hairy cell leukemia were treated with biosynthetic (recombinant) alpha-2-interferon in an open-label, single- arm efficacy study. Patients received 2 X 10(6) U/m2 recombinant alpha- 2-interferon three times weekly. Therapy was well tolerated subjectively with minimal short-term hematologic toxicity.
A D, Jacobs, R E, Champlin, D W, Golde
openaire +3 more sources
The value of interferon therapy for COVID-19 in children
Детские инфекции (Москва), 2021 The article presents a literature review, which provides data on the role of interferons in the immunopathogenesis of COVID-19 and the clinical efficacy of drugs based on recombinant interferon-alpha 2b in the treatment of children with new coronavirus ...
L. N. Mazankova +2 more
doaj +1 more source
Enhanced anti-HCV activity of interferon alpha 17 subtype
Virology Journal, 2009 Background Pegylated interferon alpha 2 (a or b) plus ribavirin is the most effective treatment of chronic hepatitis C but a large proportion of patients do not respond to therapy. So, it is interesting to improve the treatment efficacy. Interferon alpha
Dubuisson Jean +7 more
doaj +1 more source
Antiviral Activity of Interferon Alpha-2b and Taurine Combination Against SARS-CoV-2 in vitro
Антибиотики и Химиотерапия, 2022 Interferons (IFN) have antiviral activity against many viruses, including SARS-CoV-2. A combination of IFN-a2b and the antioxidant taurine is widely used in the Russian Federation, and its antiviral activity has not been studied before.
N. P. Kartashova +5 more
doaj +1 more source