Results 31 to 40 of about 25,282,834 (298)

Muir-Torre syndrome - Treatment with isotretinoin and interferon alpha-2a can prevent tumour development [PDF]

, 2000
Muir-Torre syndrome is a genodermatosis in which multiple internal malignancies are associated with cutaneous sebaceous tumours and kerato-acanthomas. A 57-year-old man presented with multiple sebaceous tumours, kerato-acanthomas, verrucous carcinoma of ...
Graefe, Tim, Burgdorf, Walter H. C., Wollina, Uwe, Schulz, Hans-Joachim   +3 more
core   +1 more source

PROTEIN-PROTEIN INTERACTION ANALYSIS OF HUMAN INTERFERON ALPHA RECEPTOR 2 (IFNAR-2) PROTEIN USING STRING SERVER

Pakistan Armed Forces Medical Journal, 2020
Objective: To study the functional and molecular interactions of IFNAR-2 within biological networks Study Design: Computational analysis: STRING software Place and Duration of Study: Department of Biochemistry, HITEC-Institute of Medical Sciences,
Gulshan Ara Trali, Ambreen Javed, Alia Sadiq   +2 more
doaj   +4 more sources

Differential regulation of surface receptor expression, proliferation, and apoptosis in HaCaT cells stimulated with interferon-γ, interleukin-4, tumor necrosis factor-α, or muramyl dipeptide

International Journal of Immunopathology and Pharmacology, 2017
Keratinocytes are routinely subjected to both internal and external stimulation. This study investigates the effects of interferon gamma, interleukin-4, tumor necrosis factor alpha, and the synthetic immunomodulator muramyl dipeptide on the human ...
Emale El Darzi, Samer Bazzi, Sarah Daoud, Karim S Echtay, Georges M Bahr   +4 more
doaj   +1 more source

IN SILICO CHARACTERIZATION OF HUMAN INTERFERON ALPHA/BETA RECEPTOR 2 (ISOFORM A, B AND C) PROTEIN

Pakistan Armed Forces Medical Journal, 2021
Objective: To predict the tertiary structure of human interferon alpha/beta receptor 2 protein. Study Design: Structure prediction by using bio informatics tools. Place and Duration of Study: Department of Biochemistry, Swat Medical College (STMC),
Ambreen Javed, Gulshan Ara Trali, Hassan Burair Abbas, Alia Sadiq   +3 more
doaj   +3 more sources

Tratamento de hemangioma gigante com interferon alfa: relato de dois casos Treatment of giant hemangioma with interferon-alpha: report of two cases

Revista Brasileira de Hematologia e Hemoterapia, 2007
O objetivo do trabalho é descrever o uso de interferon alfa no tratamento de pacientes com hemangioma gigante. Os autores relatam e analisam dois casos de hemangioma gigante em tratamento com interferon alfa. IBS, 3 anos, em acompanhamento no Ambulatório
Ana Julia Balau, Livia C. De Nadai, Mônica S. Bressan, Josiane L. Simão   +3 more
doaj   +1 more source

Human interferon-alpha A, -alpha 2, and -alpha 2(Arg) genes in genomic DNA

Journal of Biological Chemistry, 1993
The frequency in human genomic DNA of three human interferon (IFN) alpha genes which differ from each other by a single base substitution was examined in 11 normal individuals. The polymerase chain reaction (PCR) was used to amplify the coding sequence for the Hu-IFN-alpha 2, Hu-IFN-alpha A, and Hu-IFN-alpha 2(Arg) sequences from genomic DNA.
S L, Emanuel, S, Pestka
openaire   +2 more sources

Interferon signaling in chronic hepatitis C : mechanisms and implications for therapy [PDF]

, 2008
Hepatitis C virus (HCV) infection is a major cause of chronic liver disease worldwide and can lead to liver cirrhosis and hepatocellular carcinoma.
Sarasin-Filipowicz, Magdalena
core   +1 more source

TNFα aggravates detrimental effects of SARS-CoV-2 infection in the liver

Frontiers in Immunology, 2023
Coronavirus disease 2019 (COVID-19) is caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). This virus does not only lead to pulmonary infection but can also infect other organs such as the gut, the kidney, or the liver.
Jöran Lücke, Jöran Lücke, Jöran Lücke, Mikolaj Nawrocki, Mikolaj Nawrocki, Mikolaj Nawrocki, Josa Schnell, Josa Schnell, Nicholas Meins, Nicholas Meins, Fabian Heinrich, Fabian Heinrich, Tao Zhang, Tao Zhang, Franziska Bertram, Franziska Bertram, Franziska Bertram, Morsal Sabihi, Morsal Sabihi, Marius Böttcher, Marius Böttcher, Marius Böttcher, Tom Blankenburg, Tom Blankenburg, Marie Pfaff, Sara Notz, Jan Kempski, Jan Kempski, Jan Kempski, Jan Kempski, Matthias Reeh, Stefan Wolter, Oliver Mann, Jakob R. Izbicki, Marc Lütgehetmann, Anna Duprée, Anastasios D. Giannou, Anastasios D. Giannou, Anastasios D. Giannou, Benjamin Ondruschka, Samuel Huber, Samuel Huber, Samuel Huber   +42 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Association of IFNL3 rs12979860 and rs8099917 with biochemical predictors of interferon responsiveness in chronic hepatitis C virus infection [PDF]

, 2013
Background & Aims: Genetic variations near the interferon lambda 3 gene (IFNL3, IL28B) are the most powerful predictors for sustained virologic response (SVR) in patients with chronic hepatitis C virus (HCV) infection, compared to other biochemical or ...
Simone Susser (48294), Annika Brodzinski, Thomas Berg (186372), Migaud, Pascal, Jacob George (205614), Brodzinski, Annika, Tobias Müller, Susser, Simone, Stephan Böhm (334611), Sarrazin, Christoph, Christoph Sarrazin (48298), Pascal Migaud, Schott, Eckart, Bömmel, Florian van, Heiko Witt, Florian van Bömmel, Janett Fischer, Christoph Sarrazin, Stewart, Graeme, Graeme Stewart, Witt, Heiko, Thomas Berg, Simone Susser, Balazs Fülöp, Fülöp, Balazs, Stephan Böhm, Annika Brodzinski (477753), Balazs Fülöp (477754), Müller, Tobias, Fischer, Janett, Böhm, Stephan, Berg, Thomas, Tobias Müller (163591), Janett Fischer (477751), Eckart Schott (320945), Graeme Stewart (208243), Jacob George, Heiko Witt (161481), Pascal Migaud (477752), George, Jacob, Eckart Schott, Florian van Bömmel (477755)   +41 more
core   +1 more source