Results 21 to 30 of about 25,282,834 (298)

The regulation of type I interferon production by paramyxoviruses [PDF]

, 2009
Research supported by The Wellcome Trust (087751/A/08/Z)Experimentally, paramyxoviruses are conventionally considered good inducers of type I interferons (IFN-alpha/beta), and have been used as agents in the commercial production of human IFN-alpha ...
Goodbourn, S, Richard E. Randall, Stephen Goodbourn, Randall, Richard Edward   +3 more
core   +1 more source

Interferon impedes an early step of hepatitis delta virus infection. [PDF]

PLoS ONE, 2011
Hepatitis delta virus (HDV) infects hepatocytes, the major cell type of the liver. Infection of the liver may be either transient or chronic. The prognosis for patients with chronic HDV infection is poor, with a high risk of cirrhosis and hepatocellular ...
Ziying Han, Shoko Nogusa, Emmanuelle Nicolas, Siddharth Balachandran, John Taylor   +4 more
doaj   +1 more source

Epstein-Barr Virus LF2: an Antagonist to Type 1 Interferon [PDF]

, 2009
Upon viral infection, the major defense mounted by the host immune system is activation of the interferon (IFN)-mediated antiviral pathway, which is mediated by IFN regulatory factors (IRFs).
Shin, Young Chul, Johannsen, Eric, Haas, Juergen, Hyun Joo, Chul, Fossum, Even, Hutt-Fletcher, Lindsay M., Wu, L., Inn, Kyung-Soo, Jung, Jae U.   +8 more
core   +1 more source

Treatment of hairy cell leukemia with recombinant alpha 2 interferon [PDF]

Blood, 1985
Abstract Nine patients with progressive hairy cell leukemia were treated with subcutaneous injections of recombinant alpha 2 interferon (2 to 10 X 10(6) U/m2) three times weekly. Eight patients completed at least eight weeks of treatment and were evaluable; one patient with refractory thrombocytopenia died of an intracerebral hemorrhage ...
M J, Ratain, H M, Golomb, J W, Vardiman, E E, Vokes, R H, Jacobs, K, Daly   +5 more
openaire   +3 more sources

Vaginal biocenosis in pregnant women with recurrent bacterial vaginosis after treatment with recombinant human interferon alpha-2b

Акушерство, гинекология и репродукция, 2019
Introduction. Preventing recurrent bacterial vaginosis (BV) during pregnancy is an important issue in current obstetrics.Aim: to assess the effect of recombinant human interferon alpha-2b on the incidence of recurrent BV during pregnancy and on the ...
A. V. Podgornaya, A. Sh. Makhmutkhodzhaev   +1 more
doaj   +1 more source

Genome-wide expression profiling identifies type 1 interferon response pathways in active tuberculosis [PDF]

, 2012
Contains fulltext : 108027.pdf (Publisher’s version ) (Open Access)Tuberculosis (TB), caused by Mycobacterium tuberculosis (M.tb), remains the leading cause of mortality from a single infectious agent.
Crevel, R. van, van Crevel, R., Hazel E E Wong, Sahiratmadja Edhyana, Zhang, M.M., Wong, Hazel EE, Ottenhoff, THM, van de Vosse, Esther, Yang, N., Ottenhoff, T.H., Martin L Hibberd, Ottenhoff Tom H. M., Khor C.C., Dass, Ranjeeta, Reinout van Crevel, Hibberd M.L., van Crevel Reinout, Dass R.H., Yang, N, Chiea Chuen Khor, Khor, C.C., Seielstad, M., Zhang Mingzi M., van de Vosse E., Zhang M.M., Ottenhoff, Tom HM, Tom H M Ottenhoff, van Crevel, Reinout, Ottenhoff, T.H.M., Yang, Ninghan, Sahiratmadja, Edhyana, Wong, H.E., Seielstad M., Sahiratmadja E., Alisjahbana Bachti, Marzuki, Sangkot, van Crevel R., Khor, CC, Edhyana Sahiratmadja, Bachti Alisjahbana, Yang Ninghan, Alisjahbana, B., Hibberd, M.L., Ninghan Yang, Alisjahbana, Bachti, van, R, van de Vosse, E., Wong, Hazel, Dass Ranjeeta Hari, Alisjahbana, B, Ranjeeta Hari Dass, Hibberd, Martin, Yang, N.H., Sangkot Marzuki, Dass, Ranjeeta Hari, Seielstad Mark, Khor Chiea Chuen, Ottenhoff, Tom, Marzuki, S., Dass, RH, Hibberd Martin L., Marzuki, S, Wong H.E.E., Marzuki S., Zhang, M.Z.M., Zhang, MM, Khor, Chiea, van de Vosse Esther, Khor, Chiea Chuen, Mark Seielstad, Vosse, E. van de, Marzuki Sangkot, Sahiratmadja, E., Dass, R.H., Yang N., Zhang, Mingzi, Seielstad, Mark, Wong, HEE, Hibberd, Martin L, Sahiratmadja, E, Ottenhoff T.H.M., Zhang, Mingzi M, Esther van de Vosse, Alisjahbana B., Wong Hazel E. E., Wong, H.E.E., Mingzi M Zhang   +86 more
core   +3 more sources

Intranasal interferon-alpha 2 for prevention of natural rhinovirus colds [PDF]

Antimicrobial Agents and Chemotherapy, 1984
The prophylactic activity of intranasal human interferon-alpha 2 (HuIFN-alpha 2) against natural rhinovirus colds was determined in a randomized, double-blind, placebo-controlled trial. A total of 304 working adults self-administered sprays of HuIFN-alpha 2 (10(7) IU/day) or a placebo once daily.
B M, Farr, J M, Gwaltney, K F, Adams, F G, Hayden   +3 more
openaire   +2 more sources

Bunyaviruses and the type I interferon system [PDF]

, 2009
The family Bunyaviridae contains more than 350 viruses that are distributed throughout the world. Most members of the family are transmitted by arthopods, and several cause disease in man, domesticated animals and crop plants. Despite being recognized as
Richard M. Elliott, Weber, F., Richard Elliott, Richard M. Elliott, Elliott, Richard Michael, Friedemann Weber, Weber, F, Elliott, R.M.   +7 more
core   +1 more source

Mapuera virus, a rubulavirus that inhibits interferon signalling in a wide variety of mammalian cells without degrading STATs [PDF]

, 2007
Majouera virus (MPRV) is a paramyxovirus that was originally isolated from bats, but its host range remains unknown. It was classified as a member of the genus Rubulavirus on the basis of structural and genetic features.
Goodbourn, S, Childs, K, Randall, RE, Precious, B, Stock, N, Wang, LF, Hagmaier, K, Randall, Richard Edward, Wang, L-F   +8 more
core   +1 more source

CLINICAL AND IMMUNOLOGICAL EFFICIENCY OF INTERFERON ALPHA_2 AS A PART OF COMPLEX THERAPY OF CHILDREN, SUFFERING FROM THE LINGERING RECURRENT FORMS OF PSEUDOTUBERCULOSIS

Педиатрическая фармакология, 2007
The researchers have examined 45 children aged between 3 and 14, suffering from the lingering recurrent forms of pseudotuberculosis. 25 children (55,6%) received some conventional therapy, whereas 20 patients (44,3%) used interferon alpha_2. The practice
V.N. Timchenko, N.M. Kalinina, I.V. Babachenko, E.B. Pavlova, T.K. Strebunova, E.V. Barakina   +5 more
doaj   +2 more sources