Results 31 to 40 of about 50,714 (355)

Interferons, Interferon Inducers, and Interferon-Ribavirin in Treatment of Flavivirus-Induced Encephalitis in Mice [PDF]

Antimicrobial Agents and Chemotherapy, 2003
ABSTRACT We evaluated the prophylactic and therapeutic efficacy of interferon α-2b, pegylated interferon α-2b, poly(I · C), and Ampligen against Modoc virus encephalitis in an animal model for flavivirus infections. All compounds significantly delayed virus-induced morbidity (paralysis) and mortality (due to progressive encephalitis).
Pieter, Leyssen, Christian, Drosten, Marcus, Paning, Nathalie, Charlier, Jan, Paeshuyse, Erik, De Clercq, Johan, Neyts   +6 more
openaire   +2 more sources

Interferon Status and Choice of Interferons Inducers in Frequently Ill Children

Детские инфекции (Москва), 2016
Literature data on the study of interferon status in children. Own results of the survey group of frequently ill children (FIC) have shown insufficient production of IFN alpha and gamma-IFN, humoral immunity. It was revealed that 66% of the group FIC has
M. S. Savenkovа, O. V. Karashtinа, M. B. Shabat, G. N. Kraseva, N. A. Abramova, T. E. Kraseva   +5 more
doaj   +1 more source

Differential induction of TLR3-dependent innate immune signaling by closely related parasite species. [PDF]

PLoS ONE, 2014
The closely related protozoan parasites Toxoplasma gondii and Neospora caninum display similar life cycles, subcellular ultrastructure, invasion mechanisms, metabolic pathways, and genome organization, but differ in their host range and disease ...
Daniel P Beiting, Lucia Peixoto, Natalia S Akopyants, Stephen M Beverley, E John Wherry, David A Christian, Christopher A Hunter, Igor E Brodsky, David S Roos   +8 more
doaj   +1 more source

Study of the Activity of Antiviral Drugs Against the Causative Agent of Chikungunya Fever in Cell Culture

Антибиотики и Химиотерапия, 2023
Сhikungunya  virus (CHIKV) is a member of the Flavivirus genus, Flaviviridae family. It belongs to the zoonotic arbovirus infections transmitted by mosquitoes of the genus Aedes.
S. Ya. Loginova, V. N. Schukina, S. V. Savenko, R. V. Sakharov, S. V. Borisevich   +4 more
doaj   +1 more source

Sequential Interferon β-Cisplatin Treatment Enhances the Surface Exposure of Calreticulin in Cancer Cells via an Interferon Regulatory Factor 1-Dependent Manner

Biomolecules, 2020
Immunogenic cell death (ICD) refers to a unique form of cell death that activates an adaptive immune response against dead-cell-associated antigens. Accumulating evidence indicates that the efficacy of conventional anticancer agents relies on not only ...
Pei-Ming Yang, Yao-Yu Hsieh, Jia-Ling Du, Shih-Chieh Yen, Chien-Fu Hung   +4 more
doaj   +1 more source

The effect of multiprobiotic “Apibact®” on interferon production and 2',5'-oligoadenylate synthetase activity in rat thymus lymphocytes under hypoacidity evoked by omeprazole injection

Біологічні студії, 2013
The interferon (IFN) production by rat thymus lymphocytes and the activity of IFN-induced 2′,5′-oligoadenylate synthetase (2′,5′-OA-synthetase) in these cells were stu­died at hypoacidity of gastric juice evoked by omeprazole injection and also at ...
I. V. Kompanets, S. V. Pilipenko, A. G. Korotkiy, T. P. Karpovets, V. V. Nikolska, L. I. Ostapchenko, T. V. Beregova, D. S. Yankovskiy   +7 more
doaj   +1 more source

M-DC8+leukocytes - A novel human dendritic cell population [PDF]

, 1999
Dendritic cells (DC) constitute a heterogeneous leukocyte population having in common a unique capacity to induce primary T cell responses and are therefore most attractive candidates for immunomodulatory strategies.
Federle, Christine, Mayer, Elfriede, Poppe, Claudia, Rieber, Ernst Peter, Riethmüller, Gert, Schäkel, Knut   +5 more
core   +2 more sources

ADJUVANT THERAPY FOR RECURRENT RESPIRATORY PAPILLOMATOSIS IN CHILDHOOD

Педиатрическая фармакология, 2006
The article outlines etiology, pathogenesis, clinical course, diagnostic, therapeutic and surgical treatment of recurrent respiratory papillomatosis (RRP) in childhood.
Yu.L. Soldatskiy
doaj   +2 more sources

INFLUENZA AND OTHER ACUTE RESPIRATORY INFECTIONS: CURRENT PRINCIPLES AND TREATMENT PRACTICE

Медицинский совет, 2017
In the Russian Federation, the incidence of influenza and other acute viral respiratory infections (ARVI) increases every year during the autumn-winter period. The most common ARVI are parainfluenza, adenoviral and respiratory-syncytial infection.
G. N. Karetkina
doaj   +1 more source

Forging a potent vaccine adjuvant: CpG ODN/cationic peptide nanorings [PDF]

, 2014
Cataloged from PDF version of article.Type I interferon inducers may potentially be engineered to function as antiviral and anticancer agents, or alternatively, vaccine adjuvants, all of which may have clinical applications.
Gungor, B., Gursel, I., Gursel, M., Yagci, F. C.   +3 more
core   +1 more source