Results 21 to 30 of about 201,455 (289)
Efficacy of interferon inducers against Chikungunya virus in vitro
Биопрепараты: Профилактика, диагностика, лечение, 2023 Scientific relevance. To date, no specific antivirals have been approved to treat and prevent Chikungunya fever, its complications, and sequelae. Therefore, the development of therapeutic and preventive medicinal products against Chikungunya virus (CHIKV)
E. V. Otrashevskaja +4 more
doaj +1 more source
Interferons, Interferon Inducers, and Interferon-Ribavirin in Treatment of Flavivirus-Induced Encephalitis in Mice [PDF]
Antimicrobial Agents and Chemotherapy, 2003 ABSTRACT We evaluated the prophylactic and therapeutic efficacy of interferon α-2b, pegylated interferon α-2b, poly(I · C), and Ampligen against Modoc virus encephalitis in an animal model for flavivirus infections. All compounds significantly delayed virus-induced morbidity (paralysis) and mortality (due to progressive encephalitis).
Pieter, Leyssen +6 more
openaire +2 more sources
Interferon-induced sarcoidosis [PDF]
BMJ Case Reports, 2011 Sarcoidosis is a rare side effect of interferon therapy that has been reported over the last years. We present the case of a 43-year-old man presenting with systemic sarcoidosis during treatment with pegylated interferon and ribavirin. Skin lesions, which were found to be associated with asymptomatic bilateral hilar lymph nodes and pulmonary nodules ...
Cláudia, Cardoso +3 more
openaire +2 more sources
Interferon induced thyroiditis [PDF]
Best Practice & Research Clinical Endocrinology & Metabolism, 2009 Interferon-alpha (IFNalpha) is used for the treatment of various disorders, most notable chronic hepatitis C virus (HCV) infection. One of the commonest side effects of IFNalpha therapy is thyroiditis, with up to 40% of HCV patients on IFNalpha developing clinical or subclinical disease.
Yaron, Tomer, Francesca, Menconi
openaire +2 more sources
Journal of General Virology, 1972 Summary The pre-treatment of mouse L cells with interferon or polyinosinic-polycytidylic acid potentiated the interferon response of these cells to subsequent stimulation with suboptimal doses of polyinosinic-polycytidylic acid. This potentiation was manifested as an earlier production of interferon, a faster attainment of maximum interferon production,
S A, Margolis, H, Oie, H B, Levy
openaire +2 more sources
Effect of Interferon Inducers and Interferon on Bacterial Infections [PDF]
Antimicrobial Agents and Chemotherapy, 1972 The effect of interferon inducers and exogenous L-cell interferon on the infection of mice by Pasteurella tularensis or Diplococcus pneumoniae was investigated. The results indicate that the degree of protection is dependent on the type of inducer used.
D J, Giron +3 more
openaire +2 more sources
Laureates of the Palladin Prize of the National Academy of Sciences of Ukraine (2008, 2011) [PDF]
The Ukrainian Biochemical Journal, 2014 In 2008 Z. R. Ulberg, O. V. Karpov and S. V. Veryovka were awarded the Palladin Prize of NAS of Ukraine for the series of scientific works “Colloid-chemical and physical-biochemical aspects of the interaction of nano- and microparticles with cells as a ...
R. P. Vynogradova, V. M. Danilova
doaj +1 more source
The N-terminus of Bunyamwera orthobunyavirus NSs protein is essential for interferon antagonism [PDF]
, 2010 This work is supported by UK MRC and BBRCBunyamwera virus NSs protein is involved in the inhibition of cellular transcription and the interferon (IFN) response, and it interacts with the Med8 component of Mediator.
Van Knippenberg, Ingeborg Christine +5 more
core +1 more source
Interferon signalling in the liver : implications for the natural course and therapy of hepatitis C [PDF]
, 2012 Hepatitis C virus is a global health concern, estimated to infect 2-3% of the world's population. Inter-individual differences in the course of infection and response to therapy, highlighted by recent genomewide association studies, point to the crucial ...
Makowska, Zuzanna
core +1 more source
Ветеринария сегодня, 2018 Today studies of the influence of interferon synthesis inducer on human and animal body is a topical issue. Interferon synthesis inducers are substances of natural or artificial origin stimulating production of body’s own interferon. One of the synthetic
D. V. Sharypova +6 more
doaj +1 more source