Results 1 to 10 of about 37,759 (197)
Interferon and Interferon Inducers in Protozoal Infections [PDF]
Journal of General Physiology, 1970 Several interferon inducers (Newcastle disease virus, statolon, and poly rI:poly rC) as well as exogenous mouse interferon protect mice from sporozoite-induced Plasmodium berghei malaria, as long as they are administered before the end of the preerythrocytic phase of development of the parasite.
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Nonviral Interferon Inducers [PDF]
Journal of General Physiology, 1970 Interferon production can be stimulated by a great variety of microbial and nonmicrobial agents other than viruses. The nonmicrobial inducers can be divided into polyanions, mitogens, and a miscellaneous category including the various endotoxins and antibiotics.
Erik De Clercq, T C Merigan
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Interferon and Interferon Inducers in the Treatment of Malignancies [PDF]
Archives of Internal Medicine, 1970 Several laboratories have reported that viral interference, 1 interferon, 2 and interferon inducers 3,4 can inhibit the growth of oncogenic viruses in tissue culture, 5 and can alter the course of murine leukemias in animals. 6,7 It has also been shown that the double-stranded RNA, polyriboinosinic: polyribocytidylic acid (poly I:C), which among other ...
H B, Levy, F, Riley, S, Margolis
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Инфекция и иммунитет, 2021 Here, we review an overall effectiveness of interferon-based preparations and interferon biosynthesis inducers for treatment of feline leukemia, as well as development of methodological approaches to improve efficacy of interferon therapy.
T. V. Moskvina +2 more
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Evaluation of the effectiveness of ARVI treatment regimen including etiotropic (enisamium iodide) and symptomatic treatment [PDF]
Терапевтический архив, 2020 Aim. To assess the effectiveness of the use of the antiviral drug enisamium iodide in the complex treatment of acute respiratory viral infections (ARVI) caused by various pathogens in routine clinical practice. Materials and methods.
D. A. Lioznov +3 more
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Efficacy of interferon inducers against Chikungunya virus in vitro
Биопрепараты: Профилактика, диагностика, лечение, 2023 Scientific relevance. To date, no specific antivirals have been approved to treat and prevent Chikungunya fever, its complications, and sequelae. Therefore, the development of therapeutic and preventive medicinal products against Chikungunya virus (CHIKV)
E. V. Otrashevskaja +4 more
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Innate Intracellular Antiviral Responses Restrict the Amplification of Defective Virus Genomes of Parainfluenza Virus 5. [PDF]
, 2020 During the replication of parainfluenza virus 5 (PIV5), copyback defective virus genomes (DVGs) are erroneously produced and are packaged into "infectious" virus particles.
Goodbourn, S +6 more
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Interferon-induced sarcoidosis [PDF]
BMJ Case Reports, 2011 Sarcoidosis is a rare side effect of interferon therapy that has been reported over the last years. We present the case of a 43-year-old man presenting with systemic sarcoidosis during treatment with pegylated interferon and ribavirin. Skin lesions, which were found to be associated with asymptomatic bilateral hilar lymph nodes and pulmonary nodules ...
Cláudia, Cardoso +3 more
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Interferon induced thyroiditis [PDF]
Best Practice & Research Clinical Endocrinology & Metabolism, 2009 Interferon-alpha (IFNalpha) is used for the treatment of various disorders, most notable chronic hepatitis C virus (HCV) infection. One of the commonest side effects of IFNalpha therapy is thyroiditis, with up to 40% of HCV patients on IFNalpha developing clinical or subclinical disease.
Yaron, Tomer, Francesca, Menconi
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Interferons, Interferon Inducers, and Interferon-Ribavirin in Treatment of Flavivirus-Induced Encephalitis in Mice [PDF]
Antimicrobial Agents and Chemotherapy, 2003 ABSTRACT We evaluated the prophylactic and therapeutic efficacy of interferon α-2b, pegylated interferon α-2b, poly(I · C), and Ampligen against Modoc virus encephalitis in an animal model for flavivirus infections. All compounds significantly delayed virus-induced morbidity (paralysis) and mortality (due to progressive encephalitis).
Pieter, Leyssen +6 more
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