Results 191 to 200 of about 171,612 (313)

Interferon signaling and STING pathway in head and neck cancers: unlocking immune secrets and therapeutic frontiers. [PDF]

Cancer Cell Int
Zolfaghari K, Yazdi M, Mohammadioun S, Tajafrooz F, Malekfarnood H, Saleki K, Rezaei N.   +6 more
europepmc   +1 more source

Additional file 1: Table S1. of CXC chemokine superfamily induced by Interferon-Îł in asthma: a cross-sectional observational study

, 2016
Yotaro Takaku, Tomoyuki Soma, Yoshitaka Uchida, Takehito Kobayashi, Kazuyuki Nakagome, Makoto Nagata   +5 more
openalex   +1 more source

Skeletal Muscle HSF1 Alleviates Age‐Associated Sarcopenia and Mitochondrial Function Decline via SIRT3‐PGC1α Axis

Advanced Science, EarlyView.
Aged HSF1 muscle‐specific knockout mice show deteriorated muscle atrophy and metabolic dysfunction, while active HSF1 overexpression improves muscle function via activating SIRT3 to deacetylate both PGC1α1 and PGC1α4, which boosts mitochondrial function and muscle hypertrophy in a fiber‐type specific manner, and induces FNDC5/Irisin for tissue ...
Jun Zhang, Min Hu, Xia Wu, Mingwei Guo, Ying Ma, Jin Qiu, Siqi Wang, Yuxiang Cao, Yinzhao Zhong, Fangfang Chen, Yiwen Wang, Wei Wei, Yan Lu, Yong Zhang, Junjie Xiao, Zhenji Gan, Cheng Hu, Xinran Ma, Lingyan Xu   +18 more
wiley   +1 more source

Type I interferons increase expression of endogenous retrovirus K102 and envelope protein in myeloid cells from patients with autoimmune disease. [PDF]

Mob DNA
Le E, Moadab F, Wang X, Najjar R, Bays A, Hastie KM, Shek J, Saphire EO, Mustelin T.   +8 more
europepmc   +1 more source

Type I Interferon Pathway Activation Disrupts Monocyte Maturation and Enhances Immune Evasion in Multiple Myeloma

Advanced Science, EarlyView.
This study shows that monocytes in multiple myeloma display an excessive interferon response, leading to transcriptional reprogramming and altered differentiation. Using single‐cell sequencing, coculture experiments, and patient samples before and after therapy, the authors demonstrate that induction treatment reduces this interferon response ...
Jian Cui, Jingwei Wang, Xiaoyun Li, Lina Wang, Xuehan Mao, Rui Lyv, Wenqiang Yan, Jingyu Xu, Jieqiong Zhou, Chenxing Du, Shuhui Deng, Mu Hao, Yan Xu, Shuhua Yi, Dehui Zou, Tao Cheng, Xin Gao, Lugui Qiu, Gang An   +18 more
wiley   +1 more source

Exosomes derived from avian influenza virus-infected chickens modulate host immune responses. [PDF]

Poult Sci
Kim C, Phan TH, Truong AD, Hong YH.
europepmc   +1 more source

Cyclin E1 overexpression triggers interferon signaling and is associated with antitumor immunity in breast cancer [PDF]

Shibo Yu, Chantal Stappenbelt, Mengting Chen, Matthew Dekker, Arkajyoti Bhattacharya, Tineke van der Sluis, Mieke C. Zwager, Carolien P. Schröder, Rudolf S.N. Fehrmann, Marcel A.T.M. van Vugt, Bert van der Vegt   +10 more
openalex   +1 more source

Characterizing Stage‐Specific Cellular Dynamics and Microenvironmental Remodeling in Lung Adenocarcinoma by Single‐Cell RNA Sequencing

Advanced Science, EarlyView.
This study integrated early‐stage patient specimens with publicly available datasets encompassing non‐malignant lung tissues and advanced‐stage LUAD through single‐cell sequencing, revealing a dynamically remodeled tumor microenvironment characterized by a hypoxia‐adapted malignant subset (C5), immunosuppressive LGMN+ macrophages, STAT1‐driven ...
Bomiao Qing, Xiaolan Li, Xiang He, Junyi Wang, Yi Yang, Manling Jiang, Bingbing Yan, Lei Zhang, Anying Xiong, Qin Ran, Guoping Li   +10 more
wiley   +1 more source

Mechanism by which porcine transmissible gastroenteritis virus disrupts host innate immunity. [PDF]

Front Immunol
Wang Z, Xie J, Li Q, Liu Y, Zhang X, Mi E, Wang L, Wang L, Zhang F.   +8 more
europepmc   +1 more source

PEP-R619W Distinctly Modulates Persistent Type-I Interferon Signaling to enhance DC and CD8 T cell function 4147 [PDF]

Anam Fatima Shaikh, Jenna Barnes, Tammy Cockerham, Nancy Schwarting, Robin C. Orozco   +4 more
openalex   +1 more source