Results 161 to 170 of about 30,772 (210)

Interaction with NEGR1 affects mGlu5 cell signalling and the neuroprotection induced by the positive allosteric modulator VU0409551

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and Purpose The metabotropic glutamate receptor mGlu5 plays an important role in neuronal survival and synaptic plasticity. We and others have shown that mGlu5 positive allosteric modulators (PAMs) are biased agonists, triggering the activation of neuroprotective pathways and promoting neuronal survival. As mGlu5 biased pharmacology
Jennifer D. S. Guimaraes   +14 more
wiley   +1 more source

Epidemiological and Prognostic Differences in Malignant Mesothelioma Between Eastern China and SEER Database

open access: yesCancer Science, EarlyView.
For long years, patients and clinicians in Eastern China used Western data as information foundation for management and treatment of malignant mesothelioma, due to its rarity and lack of deep investigation. This study updated the epidemiological data of malignant mesothelioma in Eastern China, and revealed better survival outcomes compared to Western ...
Ningning Li   +7 more
wiley   +1 more source

Correcting Axial Length‐Related Magnification Errors in Optical Coherence Tomography Angiography Improves Machine Learning Classification Performance in High Myopia

open access: yesClinical &Experimental Ophthalmology, EarlyView.
ABSTRACT Background To determine whether axial length‐related magnification correction in optical coherence tomography angiography (OCTA) improves machine learning classification of high myopia and resolves inconsistencies in the values and discriminatory power of OCTA microvascular metrics.
Danuta M. Sampson   +9 more
wiley   +1 more source

Assessing patient perception following outpatient dermatological surgical procedures

open access: yesJDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Background and objectives Despite receiving similar information about outpatient dermatologic surgical procedures, some patients still hold misconceptions about the nature of their lesions and the treatment. No studies have been done to understand this difference in the perception of surgery.
Ana Morelló‐Vicente   +6 more
wiley   +1 more source

Muscle morphology and intramuscular fat after treatment‐as‐usual including botulinum neurotoxin A injections in children with cerebral palsy

open access: yesDevelopmental Medicine &Child Neurology, EarlyView.
Normalized muscle volume remained unchanged in all evaluated muscles after the 12‐month treatment‐as‐usual in children with cerebral palsy. Higher intramuscular fat fraction was observed in the medial gastrocnemius, suggesting concurrent intramuscular fat infiltration.
Zhongzheng Wang   +7 more
wiley   +1 more source

Home - About - Disclaimer - Privacy