Results 31 to 40 of about 456,968 (312)
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
La nueva ley de contratos del sector público: ámbito de aplicación y otras cuestiones novedosas
Revista Vasca de Administración Pública, 2007 This work analyzes some of the novelties in the the Public Sector Procurement Act 30/2007. Specifically, there are three questions to be addressed: firstly, the personal scope of the new Act, that has the singularity of starting from a generic category ...
Carmen Chinchilla Marín
doaj +2 more sources
Revista Vasca de Administración Pública, 2017 Article 56 of Act 39/2015 of October 1st, on the Common Administrative Procedure by the Public Administrations provided some novelties in the regulation of interim measures.
Belén Marina Jalvo
doaj +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
On the excessive nature of the tax authority interim measures
Вестник университетаThe study subject is the interim measures’ institute of the tax authority. The study relevance is due to the incomplete decisions’ execution of tax authorities adopted based on the results of tax audits, which leads to the excessive restrictions ...
A. V. Ilin
doaj +1 more source
Finland v. Denmark: A Call to Clarify the International Court of Justice\u27s Standards for Provisional Measures [PDF]
, 1991 This Comment argues that a prima facie showing of the existence of a right on the merits is an implicit factor that must be met by a party requesting interim relief before the Court will fully examine a request for provisional measures.
Essoff, Patricia A.
core +1 more source
AAA+ protein unfoldases—the Moirai of the proteome
FEBS Letters, EarlyView.AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
University of Bologna Law Review, 2019 This paper outlines arbitral tribunals’ power to order provisional measures under the auspices of I.C.S.I.D. Arbitration; that is, investor-state arbitration.
Ylli Dautaj, Bruno Gustafsson
doaj +1 more source
The Efficacy and Impact of Interim Measures: Ukraine’s Inter-State Application Against Russia [PDF]
, 2016 In 2013, Ukrainian President Viktor Yanukovych rejected an international agreement that had been formulated to strengthen political and economic ties between Ukraine and the European Union. A sharp divide between pro-Western and pro-Russian groups arose,
Koch, Julia
core
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source