Results 41 to 50 of about 3,083,083 (294)
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Interim Measures in Digital Markets: Interaction Between the DMA and Regulation 1/2003
Utrecht Law ReviewThis Article investigates the interplay in the field of interim measures between the Digital Markets Act (DMA) and Regulation 1/2003 on the implementation of Articles 101 and 102 TFEU competition rules.
Carla Farinhas
doaj +1 more source
Molecular Oncology, EarlyView.Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley +1 more source
Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Molecular Oncology, EarlyView.Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source
Winter Is Coming. The Polish Woodworm Games
European Papers, 2017 (Series Information) European Papers - A Journal on Law and Integration, 2017 2(3), 797-802 | Editorial | (Abstract) The political developments in Poland, which took place in course of the past two years, have brought very chilling eastern winds to ...
Adam Lazowski
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Molecular Oncology, EarlyView.High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira +7 more
wiley +1 more source
Revista Vasca de Administración Pública, 2014 Precautionary justice within the administrative contentious procedure is analyzed. Its last years¿ development and it constitutional foundations are explained.
M. Josune Pérez Estrada
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Molecular Oncology, EarlyView.Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
Interim Coastal Zone Study Committee, Galveston, Texas, January 14, 1972
, 1972 28 pagesTranscript of the Interim Coastal Zone Study Committee meeting held on January 14, 1972, in Galveston ...
Interim Coastal Zone Study Committee
core +1 more source
On the concept of interim measures in law
Legal Science and Practice: Journal of Nizhny Novgorod Academy of the Ministry of Internal Affairs of Russia, 2022 Until now the problem of interim measures from the standpoint of the general theory of law has not been studied. As a result there is no general legal definition of the concept of interim measures in law. In this publication the constituent signs of interim measures in law are proposed, on the basis of their synthesis, the author’s definition of such ...
openaire +1 more source