Results 81 to 90 of about 17,750,041 (269)
Protocol for quantifying miRNA trafficking across the endosomal membrane
FEBS Open Bio, EarlyView.An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh +2 more
wiley +1 more source
An interior proximal gradient method for nonconvex optimization
Open Journal of Mathematical OptimizationWe consider structured minimization problems subject to smooth inequality constraints and present a flexible algorithm that combines interior point (IP) and proximal gradient schemes.
De Marchi, Alberto, Themelis, Andreas
doaj +1 more source
EURO Journal on Computational Optimization, 2019 In this work, Rn we present an efficient strongly polynomial algorithm for the projection of a point on the intersection of two hyperplanes and a box in Rn.
CláudioP. Santiago +4 more
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Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank
FEBS Open Bio, EarlyView.Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer +7 more
wiley +1 more source
Interior Point Methods For Global Optimization
, 1996 Interior point methods, originally invented in the context of linear programming, have found a much broader range of applications, including global optimization problems that arise in engineering, computer science, operations research, and other ...
Mauricio G.C. Resende +2 more
core +1 more source
INTERIOR-POINT METHODS AND MODERN OPTIMIZATION CODE [PDF]
, 1999 During the last fifteen years we have witnessed an explosive development in the area of optimization theory due to the introduction and development of interior-point methods.
Lešaja, Goran
core +1 more source
BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells
FEBS Open Bio, EarlyView.BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley +1 more source
Short run hydrothermal coordination with network constraints using an interior point method
Ingeniería y Ciencia, 2008 This paper presents a lineal optimization model to solve the hydrothermal coordination problem. The main contribution of this work is the inclusion of the network constraints to the hydrothermal coordination problem and its solution using an interior ...
Jesús María López Lezama +2 more
doaj
Journal of MathematicsData completion techniques offer numerous advantages in various fields. However, completing large datasets that must satisfy specific criteria can be challenging, necessitating the use of approximative completion methods.
Hajar A. Alshaikh +2 more
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Journal of Numerical Analysis and Approximation TheoryThe focus of this research is to apply primal-dual interior-point pathfollowing methods, specifically those derived from Newton’s method for solving convex quadratic semidefinite optimization (CQSDO) problems. In this paper, we present a numerical study
Yasmina Bendaas, Mohamed Achache
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