Results 91 to 100 of about 1,470 (219)

Fe2+‐ Induced Activation of Single and Dual Metal Site—Lattice Oxygen Mechanism in Fe Rich NiFe‐LDHs for Oxygen Evolution Reaction

open access: yesAdvanced Science, EarlyView.
Fe‐rich NiFe‐LDH catalysts derived from MOFs, showing superior OER activity via lattice oxygen mechanism activation. ABSTRACT Developing a durable and efficient oxygen evolution reaction (OER) catalyst without noble metals is essential for the economical and sustainable production of hydrogen by alkaline water electrolysis.
Nithinraj Panangattu Dharmarajan   +12 more
wiley   +1 more source

MG53 Coordinates Macrophage Polarization and Neuroimmune Coupling to Promote Corneal Nerve Regeneration via the MPEG1–MVP–STAT6 Axis

open access: yesAdvanced Science, EarlyView.
Corneal nerve regeneration is critical to corneal wound healing processes. The current study reveals a novel role of MG53 in promoting corneal nerve regeneration after alkali induced injury. Mechanistically, MG53 enters macrophages via its receptor, MPEG1, promotes MVP K63 ubiquitination, and triggers STAT6 induced repair‐related genes expression ...
Peng Chen   +14 more
wiley   +1 more source

Brain and Liver Dual‐Targeting Oridonin Nanoparticles to Enhance Aβ Clearance for Alzheimer's Disease Therapy

open access: yesAdvanced Science, EarlyView.
We developed a nanoparticle named OAF, which simultaneously targeted to both the brain and liver via the transferrin receptor 1 (TfR1) receptor, promoting lipoprotein receptor‐related protein 1 (LRP1) expression to enhance amyloid‐beta (Aβ) clearance. In AD mice model, OAF significantly reduced Aβ deposition and cognitive impairment, while a mitigating
Wenshuai Gong   +8 more
wiley   +1 more source

Scanning Tunnelling Microscopy Study of Spin Interactions in Transition‐Metal Phthalocyanine Adsorbates: Mechanisms, Signatures, and Control Strategies

open access: yesAdvanced Science, EarlyView.
Transition‐metal phthalocyanine (TMPc) molecules serve as model systems for probing the spin interactions. This review summarizes recent scanning tunnelling microscopy advances on the spin‐related phenomena in TMPc adsorbates, including Kondo effect, spin excitations, and Yu–Shiba–Rusinov states, emphasizing the mechanisms and control strategies, and ...
Fudi Zhou   +6 more
wiley   +1 more source

Sono‐Mechanogenetics: Linking Ultrasound Physics With Cellular Mechanobiology

open access: yesAdvanced Science, EarlyView.
Sono‐mechanogenetics links ultrasound physics with cellular mechanotransduction to enable noninvasive control of engineered biological systems. Acoustic forces generate distinct deformation modes that activate intracellular signaling pathways, which can be coupled to synthetic gene circuits to regulate diverse cellular functions, including gene ...
Yunjia Qu   +4 more
wiley   +1 more source

Approximation of Elliptic Equations with Interior Single-Point Degeneracy and Its Application to Weak Unique Continuation Property

open access: yes
This paper investigates the quantitative weak unique continuation property (QWUCP) for a class of high-dimensional elliptic equations with interior point degeneracy. First, we establish well-posedness results in weighted function spaces. Then, using an innovative approximation method, we derive the three-ball theorem at the degenerate point.
Wu, Weijia   +3 more
openaire   +2 more sources

A High‐Throughput Live Imaging Platform to Investigate Circuit‐Dependent Regulation of Circadian Rhythms in Brain Tissue

open access: yesAdvanced Science, EarlyView.
Biological rhythms coordinate physiology, from genes to behavior. Study of circadian rhythms in brain tissue is constrained by limited throughput and spatial and temporal information quality. A new platform for high‐throughput, long‐term multiplexed fluorescent live imaging of circadian rhythms in brain slices is introduced.
Marco Ferrari   +3 more
wiley   +1 more source

In Vivo Electrochemical Monitoring of Safinamide Pharmacokinetics in the Brain Explores Its Correlation With Vision‐Related Neuronal Activity

open access: yesAdvanced Science, EarlyView.
An electrochemical platform based on differential pulse amperometry enables real‐time, selective tracking of safinamide pharmacokinetics in the living brain with high spatiotemporal resolution. When integrated with electrophysiology, this approach reveals that drug‐induced suppression of vision‐related neuronal activity provides mechanistic insight ...
Xiaoke Nan   +9 more
wiley   +1 more source

Topological Materials and Related Applications

open access: yesAdvanced Electronic Materials, EarlyView.
This review covers topological materials—including topological insulators, quantum valley Hall and quantum spin Hall insulators, and topological Weyl and Dirac semimetals—as well as their most recent advancements in fields such as spintronics, electronics, photonics, thermoelectrics, and catalysis.
Carlo Grazianetti   +9 more
wiley   +1 more source

Boron‐Doping of a Macrocyclic Tetrafuran Framework Unveils an Expanded Porphyrinoid With Switchable (Anti)Aromaticity and Conformational Dynamics

open access: yesAngewandte Chemie, EarlyView.
We disclose a novel boron macrocycle derived from the sustainable furan building block. The boraporphyrinoid exhibits a global antiaromatic ring current and dynamic conformational flexibility. Twofold reduction induces a switch to strong global aromaticity, accompanied by stiffening of the porphyrinoid backbone.
Lukas Swoboda   +6 more
wiley   +2 more sources

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