Results 71 to 80 of about 10,020,912 (301)

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

FEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro, Fernando Lucas Palhano   +1 more
wiley   +1 more source

Exploring the Potential of Floating Architecture & its Energy Challenges in the UAE [PDF]

E3S Web of Conferences
The rising issues of climate change & the increase in global population call for an intensive approach to an underutilized canvas for reimagining the way we live, work, and connect with nature.
Kartheekeyan Kamalanandhini, Baig Alvira, Mahanta Niva Rana   +2 more
doaj   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Part-level 3D shape generation driven by user intention inference with preferential Bayesian optimization

Scientific Reports
Advancements in generative artificial intelligence have introduced state-of-the-art models capable of producing impressive visual shape outputs.
Seung Won Lee, Jiin Choi, Kyung Hoon Hyun   +2 more
doaj   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

FEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito, Haduki Asano, Ayano Ueki, Joe Sakamoto, Yasuhiro Kamei, Hayato Tokumoto, Ayaka Yazawa, Shigeki Kamitani   +7 more
wiley   +1 more source

Storytelling through Interior Design: Implementing Narrative Environment Guidelines in a Hotel Main Lobby [PDF]

Narrative Environments refer to designed spaces in experiential design, where users engage with the space's storytelling and narrative, leading to atmospheric shifts. Users can comprehend and empathize with the narratives conveyed by the space, which can
Wickremasinghe, Madara, Cho, Yongyeon
core  

Interior Design Association's Constitution

, 1988
This consitution outlines the purpose and structure of the Interior Design Association.CONSTITUTION of CENTRAL PIEDMONT COMMUNITY COLLEGE INTERIOR DESIGN ASSOCIATION Article I The name of this Association is Central Piedmont Community College Interior ...
Interior Design Association
core   +1 more source

Interior design of motorway service areas on highways and international roads according to the principles of environmental sustainability

Maǧallaẗ Al-Turāṯ wa Al-Taṣmīm
Motorway service areas or rest area are defined as public facilities located next to a major road such as a motorway or a state highway, where drivers and passengers can rest, eat or refuel without exiting to secondary roads or entering cities, when ...
Prof. Saeed Hassan Abdel Rahman, Prof. Dina Fikry Gamal, Researcher. Reham Abdel Hamid Darwish   +2 more
doaj   +1 more source

Optimizing photoexcitation conditions for time‐resolved X‐ray solution scattering experiments

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering (TR‐XSS) is a powerful technique to visualize how proteins change their structure in real time after light activation. Selecting the right laser photoexcitation conditions—fluence, excitation geometry, and sample refresh rate—is critical to maximize the experimental signal while avoiding unwanted side effects ...
Matteo Levantino
wiley   +1 more source