Results 51 to 60 of about 10,020,912 (301)

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Interior Design Association

, 1988
A group photo of the Interior Design Association. It includes Lillyan Conder and Cathy Helms (President)
Interior Design Association
core   +3 more sources

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Fostering social responsibility for interior design practice [PDF]

, 2002
Tertiary interior design courses incorporating the equivalent of four years education aim to provide students with the opportunity to develop the knowledge, skills and values needed to practice as professional interior designers.
Franz, Jill M.
core  

The evolution of heritage approach in contemporary architecture and interior design from the 18th century to the 20th century

Journal of Architecture, Art & Humanistic Science
with the continuous changes in human life and the conflict between heritage and between modernity, contemporaneity and advanced technologies, we must emulate the creative thought and principles of designs used by our ancestors and mix them into what ...
Prof. Dalal Yousr-Allah Mohamed Professor of Environmental Design in Interior and Furniture Design Former Head of Decoration& Interior Architecture at The Higher Institute of Applied Arts -6th Of October, Prof. Hassan Abdo Mohamed Professor of Design at Interior Design & Furniture Department -Faculty of Applied Arts Helwan University   +1 more
doaj   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Interior Design and Comfort in Private Jets [PDF]

, 2023
Sivil havacılık endüstrisi, modern taşımacılık arasında en fazla dikkat çeken, zamandan tasarruf sağlaması açısından en çok tercih edilen ve yoğun rekabet ile birlikte, çeşitliliği ile farklılaşan hem küresel hem de ekonomik açıdan önemli sektörlerden ...
Güneş, Elif, Gürkaş, Müveddet Hanze
core   +1 more source

The impact of social customs and cultural heritages on human behavior and use of different elements of internal spaces

Journal of Architecture, Art & Humanistic Science
This research seeks to understand human behavior and its interest in interfering with the social and cultural customs of society with the aim of integrating the culture of society with acquired human behavior.
Prof. Dr. Ismael Awad Interior Design & Furniture Department – Faculty Of Applied Arts – Helwan University, Prof. Dr. Ahmed Mohamed Safi El-Din Interior Design & Furniture Department – Faculty Of Applied Arts – Banyswaif University   +1 more
doaj   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source