Results 101 to 110 of about 27,214 (254)
Archaeometry, EarlyView.Abstract This paper explores the relationship between wetland ecosystems and prehistoric lakeshore settlements within the Lake Ohrid basin (a biodiversity hotspot) by considering plant food systems at Ploča Mičov Grad, North Macedonia. The mid‐fifth millennium (c.4555–4373 to 4437–4241 cal BCE) waterlogged assemblage contained a diverse spectrum of ...
Amy Holguin +14 more
wiley +1 more source
Diabetes, Obesity and Metabolism, EarlyView.Abstract Aims Precision nutrition, guided by genetic testing, has emerged as a promising approach for managing obesity. However, robust clinical trials testing its effectiveness in real‐world dietary interventions remain scarce. The GenOn Programme aims to evaluate whether tailoring nutritional care based on genetic risk for obesity enhances weight ...
Karla P. Balbino +11 more
wiley +1 more source
Equine Veterinary Journal, EarlyView.Abstract Background The dental syndrome EOTRH is a painful, progressive dental disease with an unknown aetiology. The often painful nature of EOTRH emphasises the need for a better knowledge of the underlying pathogenic mechanism and risk factors. A comparative analysis of haematological, biochemical and endocrine values in EOTRH‐affected and non ...
Melusine Tretow +2 more
wiley +1 more source
Equine Veterinary Journal, EarlyView.Abstract Background Retrobulbar anaesthesia (RBA) is relevant for ocular surgery in standing sedated horses. Objectives Gathering insights on experiences with RBA techniques. Study Design Cross‐sectional survey. Methods An online survey collected information on the respondents' professional background, indications, injection methods, use of ultrasound ...
Simona Lieberth +4 more
wiley +1 more source
Equine Veterinary Journal, EarlyView.Abstract Background The widespread assumption that there is minimal potential for pathogen transmission between British racehorse and sport horse populations remains unverified by empirical evidence. Objectives To characterise spatiotemporal patterns of horse attendance at racing and other sport events in Great Britain in 2018.
Tegan A. McGilvray +5 more
wiley +1 more source
Mobile radio alternative systems study, executive summary [PDF]
Present day mobile communication technologies, systems and equipment are described from background in evaluating the concepts generated in the study. Average propagation ranges are calculated for terrestrial installations in each of seven physiographic ...
Anderson, R. E. +2 more
core +1 more source
TGFβ enhances platelet–breast‐cancer‐cell interaction and promotes platelet aggregation
The FEBS Journal, EarlyView.TGFβ stimulation promotes EMT in MCF7 cells, increasing their ability to bind, activate, and aggregate PLT. This effect involves the upregulation of adhesion molecules Integrin‐αv and Galectin‐3. Inhibiting Integrin‐αv or Galectin‐3, through Cilengitide and GB1103, reduces PLT adhesion to MCF7 and PLT aggregation, suggesting a mechanism linking TGFβ ...
Margherita Genitoni +7 more
wiley +1 more source
The FEBS Journal, EarlyView.Current methods to control porcine reproductive and respiratory syndrome, a disease affecting pigs, are insufficient and a safer, more effective vaccine is needed. This study describes the design and plant production of a self‐assembling protein nanoparticle vaccine candidate against this disease.
Jordan T. VanderBurgt +5 more
wiley +1 more source
The FEBS Journal, EarlyView.We characterize the PLTL lectin from Photorhabdus laumondii, which adopts a unique TNF‐like fold. Binding assays reveal a preference for branched histo‐blood group oligosaccharides. Protein crystallography uncovers a novel hexameric assembly and identifies key residues involved in carbohydrate recognition.
Filip Melicher +7 more
wiley +1 more source
Molecular basis of antibiotic sensing by the TetR family regulator CecR – a structural perspective
The FEBS Journal, EarlyView.Escherichia coli CecR, a member of the TetR family regulators, senses selected antibiotics and activates the expression of a putative drug efflux pump. Although present in many pathogenic Enterobacteriales strains, CecR remains poorly characterized. We present the first CecR crystal structure, which reveals a unique tunnel‐like ligand‐binding cavity ...
Agnieszka J. Pietrzyk‐Brzezinska +5 more
wiley +1 more source