Results 101 to 110 of about 26,452 (260)

Prenatal Cell‐Free DNA Screening With Fetal Enrichment Enables Sampling From 8 Weeks of Gestational Age

open access: yesClinical Genetics, EarlyView.
Fetal fraction (FF) estimates for 170 male pregnancies sampled between 7w0d and 9w6d of GA as a function of gestational age at blood draw without (blue triangles) and with fetal enrichment (red dots). Regression lines are shown (gray 95% CI). Besides, there is a closer look at samples below 4% FF.
Seyedeh Saideh Daryabari   +6 more
wiley   +1 more source

Investigating multimorbidity trajectories in people living with MASLD diagnosis: A trajectory analysis using the UK Biobank

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
Abstract Background Metabolic dysfunction‐associated steatotic liver disease (MASLD) is an emerging global health concern, and its presence increases the risk of multi‐system diseases. This study aimed to investigate the multimorbidity trajectories of chronic diseases in people living with MASLD.
Fang Lu   +11 more
wiley   +1 more source

Aetiological relevance of haematological, biochemical and endocrine parameters on equine odontoclastic tooth resorption and hypercementosis (EOTRH)

open access: yesEquine Veterinary Journal, EarlyView.
Abstract Background The dental syndrome EOTRH is a painful, progressive dental disease with an unknown aetiology. The often painful nature of EOTRH emphasises the need for a better knowledge of the underlying pathogenic mechanism and risk factors. A comparative analysis of haematological, biochemical and endocrine values in EOTRH‐affected and non ...
Melusine Tretow   +2 more
wiley   +1 more source

ANALISA ROUTING EIGRP(ENHANCED INTERIOR GATEWAY ROUTING PROTOCOL) DALAM JARINGAN MPLS (MULTI PROTOCOL LABEL SWITCHING ) UNTUK MENDAPATKAN KINERJA TERBAIK

open access: yes, 2017
Artikel ini merupakan versi postprint, artikel ini sudah di publikasikan pada prosiding SNASTIKOM 2017 yang dilaksanakan pada tanggal 11-12 Februari 2017 di Hotel Grand Kanaya dengan penyelenggara oleh Sekolah Tinggi Teknik Harapan Medan.
openaire   +2 more sources

Global survey on the utilisation and experiences with different retrobulbar anaesthesia techniques in horses

open access: yesEquine Veterinary Journal, EarlyView.
Abstract Background Retrobulbar anaesthesia (RBA) is relevant for ocular surgery in standing sedated horses. Objectives Gathering insights on experiences with RBA techniques. Study Design Cross‐sectional survey. Methods An online survey collected information on the respondents' professional background, indications, injection methods, use of ultrasound ...
Simona Lieberth   +4 more
wiley   +1 more source

A somatic multiple myeloma mutation unravels a mechanism of oligomerization‐mediated product inhibition in GGPPS

open access: yesThe FEBS Journal, EarlyView.
Geranylgeranyl diphosphate synthase (GGPPS) plays a key role in multiple myeloma biology. Using crystallography, mass spectrometry, and fluorescence spectroscopy, this study shows that a somatic multiple myeloma cell line mutation destabilizes inter‐dimer interactions, resulting in increased GGPPS activity by facilitating product releas.
Ruba Yehia   +7 more
wiley   +1 more source

Human Factors Ground Test Assessment and Protocol Development for Space Radiation Protection Concepts [PDF]

open access: yes
Human factors evaluations and procedures were developed in a series of ground tests in order to assess novel radiation protection concepts developed by industry leaders in aerospace.
Clowdsley, Martha   +2 more
core   +1 more source

Tks5 interactome reveals endoplasmic‐reticulum‐associated translation machinery in invadosomes

open access: yesThe FEBS Journal, EarlyView.
Invadosomes—dynamic structures enabling matrix invasion—include rosettes, dots, and linear forms, depending on cell type and context. Using the invadosome marker Tks5 (SH3PXD2A), we identified shared molecular features across cell types. Mass spectrometry revealed components of the translation machinery, notably EIF4B, and ER‐associated proteins within
Léa Normand   +11 more
wiley   +1 more source

Defining the interactome of the pancreas‐specific SPCA2 isoform (SPCA2C) identifies unique links to store‐operated Ca2+ entry

open access: yesThe FEBS Journal, EarlyView.
A BioID screen identified interacting proteins for secretory pathway calcium (Ca2+) ATPase 2C (SPCA2C) and showed new links to store‐operated Ca2+ entry. Interactions between SPCA2C and Orai1 were confirmed, along with newly identified interactions with STIM1 and CCDC47.
Petra Samardzija   +9 more
wiley   +1 more source

Propionibacterium acnes evades microbicidal phagocytosis by inhibiting the mitochondrial biogenesis of nucleus pulposus cells

open access: yesThe FEBS Journal, EarlyView.
P. acnes infection impairs the mitochondrial biogenesis of nucleus pulposus cells (NPCs) through the AMPK/SIRT‐1/PGC‐1α signaling pathway. This results in impaired mitochondria that are unable to generate sufficient ATP, and impaired delivery of mitochondrial reactive oxygen species to carry out the bactericidal process effectively.
Lemeng Ren   +9 more
wiley   +1 more source

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