Results 111 to 120 of about 26,452 (260)

Enhanced network load balancing technique for efficient performance in software defined network. [PDF]

PLoS One, 2023
Osei Kofi E, Ahene E.
europepmc   +1 more source

TGFβ enhances platelet–breast‐cancer‐cell interaction and promotes platelet aggregation

The FEBS Journal, EarlyView.
TGFβ stimulation promotes EMT in MCF7 cells, increasing their ability to bind, activate, and aggregate PLT. This effect involves the upregulation of adhesion molecules Integrin‐αv and Galectin‐3. Inhibiting Integrin‐αv or Galectin‐3, through Cilengitide and GB1103, reduces PLT adhesion to MCF7 and PLT aggregation, suggesting a mechanism linking TGFβ ...
Margherita Genitoni, Lucia Merolle, Agnese Razzoli, Eleonora Maurizi, Gaia Gavioli, Roberto Baricchi, Chiara Marraccini, Davide Schiroli   +7 more
wiley   +1 more source

Structural and functional characterization of the newly identified Photorhabdus laumondii tumor necrosis factor‐like lectin

The FEBS Journal, EarlyView.
We characterize the PLTL lectin from Photorhabdus laumondii, which adopts a unique TNF‐like fold. Binding assays reveal a preference for branched histo‐blood group oligosaccharides. Protein crystallography uncovers a novel hexameric assembly and identifies key residues involved in carbohydrate recognition.
Filip Melicher, Pavel Dobeš, Jan Komárek, Lukáš Faltinek, Marek Korsák, Petra Sýkorová, Josef Houser, Michaela Wimmerová   +7 more
wiley   +1 more source

The use of patient navigation to transition detoxification patients to substance use treatment in the Alaska Interior. [PDF]

Public Health Pract (Oxf), 2023
Running Bear U, Poole EM, Muller C, Hanson JD, Noonan C, Trojan J, Rosenman R, Manson SM.   +7 more
europepmc   +1 more source

Steering Digital Transformation: An Iterative Landscape Approach

Information Systems Journal, EarlyView.
ABSTRACT Digital transformation (DT) is in the limelight of organisations and society. However, it is challenging to steer a DT endeavour, which is also difficult to assess because of its complex nature. Instead of focusing solely on the typical end result of DT, we propose using a DT landscape approach.
Léon‐Paul de Rouw, Carol Ou, David Wodak, Henk Akkermans   +3 more
wiley   +1 more source

Factors and Strategies Influencing Integrated Self‐Management Support for People With Chronic Diseases and Common Mental Disorders: A Qualitative Study of Canadian Primary Care Nurses' Experience

Journal of Advanced Nursing, EarlyView.
ABSTRACT Aim To describe the factors influencing clinical integration of self‐management support by primary care nurses for people with physical chronic diseases and common mental disorders, as well as strategies for improvement. Design Thorne's interpretive descriptive qualitative approach.
Jérémie Beaudin, Maud‐Christine Chouinard, Émilie Hudon, Catherine Hudon   +3 more
wiley   +1 more source

Neonatal Twin Cobedding: A Mixed Method Study of Policy, Practice and Staff Perceptions in Australia

Journal of Advanced Nursing, EarlyView.
ABSTRACT Aim To explore neonatal unit policy and practice, and neonatal healthcare workers' experiences, beliefs and perceptions of twin cobedding in Australia. Design and Methods A two‐part convergent mixed methods design was used. Part 1 data were collected via an online survey of neonatal units.
Philippa Mann, Jann Foster, Kim Psaila, Virginia Schmied   +3 more
wiley   +1 more source

A Scoping Review of the Lived Experiences of Individuals With Huntington's Disease, Their Informal Caregivers and Offspring

Journal of Advanced Nursing, EarlyView.
ABSTRACT Background Huntington's disease has a disruptive effect on entire families. While previous reviews have examined lived experiences of individuals with Huntington's Disease, their informal caregivers, or their offspring, none have provided a comprehensive overview that integrates these three perspectives. Design A scoping review. Aims Providing
Cathelijn Van Baar, Kristel Kalkers, Sascha Bolt, Raymund Roos, Robbert Gobbens   +4 more
wiley   +1 more source

Emergency Nurses' Perceptions and Experiences in Managing Acute Pain in Critically Ill Adult Patients: A Qualitative Study

Journal of Advanced Nursing, EarlyView.
ABSTRACT Aim The aim of this study was to examine the perceptions and experiences of emergency nurses managing acute pain in critically ill patients. Design Qualitative descriptive study. Method Non‐participant observations (n = 46, 157 h across 10 shifts) and semi‐structured interviews (n = 30) were conducted at two Australian metropolitan emergency ...
Wayne Varndell, Margaret Fry, Doug Elliott   +2 more
wiley   +1 more source

Evaluating a Group‐Based Intervention Addressing Fear of Childbirth in Multiparous Pregnant Women: A Mixed Methods Feasibility Study

Journal of Advanced Nursing, EarlyView.
ABSTRACT Aim To assess the feasibility and acceptability of a group‐based intervention for addressing fear of childbirth in multiparous women. Design Single‐arm non‐randomised feasibility trial with a convergent mixed methods design. Methods The intervention, conducted at a central maternity hospital and led by a psychiatric nurse and a midwife ...
Laura Sandström, Marja Kaunonen, Heini Huhtala, Anna Liisa Aho   +3 more
wiley   +1 more source