Results 51 to 60 of about 27,214 (254)

Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays

FEBS Open Bio, EarlyView.
We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul, Alan Strunga, Jiri Damborsky, Zbynek Prokop   +3 more
wiley   +1 more source

Disruption of the basal body protein POC1B results in autosomal-recessive cone-rod dystrophy [PDF]

, 2014
Exome sequencing revealed a homozygous missense mutation (c.317C>G [p.Arg106Pro]) in POC1B, encoding POC1 centriolar protein B, in three siblings with autosomal-recessive cone dystrophy or cone-rod dystrophy and compound-heterozygous POC1B mutations (c ...
Arts, Heleen H, Coppieters, Frauke, Cremers, Frans PM, De Baere, Elfride, de Vrieze, Erik, den Hollander, Anneke I, Hetterschijt, Lisette, Hoyng, Carel B, Kremer, Hannie, Lambertus, Stanley, Lamers, Ideke JC, Letteboer, Stef JF, Peters, Theo A, POC1B Study Group, the, Roepman, Ronald, Roosing, Susanne, van den Born, L Ingeborgh, van Wijk, Erwin   +17 more
core   +2 more sources

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Using the redistribution between routing protocols to find best route

مجلة علوم ذي قار, 2019
Routers can forward packets through an internetwork by maintaining routing information in a database called a routing table. The routing table typically contains the address of all known networks and routing information about that network such as ...
Aqeel Hamad
doaj  

Is There Light at the Ends of the Tunnel? Wireless Sensor Networks for Adaptive Lighting in Road Tunnels [PDF]

, 2011
Existing deployments of wireless sensor networks (WSNs) are often conceived as stand-alone monitoring tools. In this paper, we report instead on a deployment where the WSN is a key component of a closed-loop control system for adaptive lighting in ...
Ceriotti, Matteo, Corrà, M., D'Orazio, Leandro, Doriguzzi, Roberto, Facchin, Daniele, Guna, Stefan, Jesi, Gianpaolo, Lo Cigno, Renato, Mottola, Luca, Murphy, Amy, Pescalli, Massimo, Picco, Gian Pietro, Pregnolato, Denis, Torghele, Carloalberto   +13 more
core   +4 more sources

Strategies to Improve the Lipophilicity of Hydrophilic Macromolecular Drugs

Advanced Healthcare Materials, EarlyView.
Hydrophilic macromolecular drugs can be successfully lipidized by covalent attachment of lipids, by hydrophobic ion pairing with negatively or positively charged surfactants, and by dry or wet reverse micelle formation. Lipophilicity enhancement of hydrophilic macromolecules has several benefits including stability and bioavailability improvement ...
Sera Lindner, Stefan Keim, Soheil Haddadzadegan, Odile Fernandez Romero, Katrin Zöller, Gabriel Stern, Ilaria Cesi, Krum Kafedjiiski, Andreas Bernkop‐Schnürch   +8 more
wiley   +1 more source

Constructing an innovative, economical and secure wireless mesh network: comparing OSPF and RIP [PDF]

, 2018
Since the invention of the internet, the number of users has been growing exponentially. The second largest continent regarding population in Africa, however, Africa is ranked fourth with the number of internet users that Africa has, despite being second
Adekunle, Andrew, McCluskey, Alex
core   +1 more source

Structural and Functional Characterization of EXPO‐Derived Extracellular Vesicles in Plants

Advanced Science, EarlyView.
In this study, 3D electron tomography (ET), cryo‐ET, and immunogold transmission electron microscopy (TEM) are employed to characterize plant extracellular vesicles (EVs) under physiological conditions. EVs are classified into three distinct categories according to their size, content, and molecular‐marker profiles. Furthermore, Exo70E2‐positive medium
Jiayang Gao, Yanbin Li, Shengqi Zhang, Yilin He, Zhiqi Liu, Juan Wang, Jingmin Hua, Jinyu Chen, Junru Zhong, Huan Zhong, Yiji Xia, Yong Cui, Liwen Jiang   +12 more
wiley   +1 more source

Analisis Unjuk Kerja Ripv2 dan Eigrp dalam Dynamic Routing Protocol [PDF]

, 2015
Jaringan komunikasi komputer didukung oleh protokol routing untuk mengirimkan paket data. Ada berbagai jenis protokol routing yang banyak digunakan, diantaranya Routing Information Protocol version 2 (RIPv2) dan Enhanced Interior Gateway Routing Protocol
Musril, H. A. (Hari)
core  

Modeling, Simulation and Emulation of Intelligent Domotic Environments [PDF]

, 2011
Intelligent Domotic Environments are a promising approach, based on semantic models and commercially off-the-shelf domotic technologies, to realize new intelligent buildings, but such complexity requires innovative design methodologies and tools for ...
Alonso, Barnett, Bonino, Bonino, Bonino, Bonino, Bonino, Booch, Carroll, Chung, Conte, Conte, Cook, Dario Bonino, Drusinsky, Fulvio Corno, Harel, HGI, Jimenez, Manesis, O. M. G. OMG, Saito, Sycara, Winer   +23 more
core   +1 more source