Results 31 to 40 of about 12,997 (305)
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
الاكاديميLighting is an important and effective element in architecture, and the reason for the individual's interaction with space and mass. Lighting design is a mixture of science and art.
In'am Ahmed Abed Shuaibi
doaj +1 more source
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Natural Lighting of Studio Apartment with East-Oriented Opening
Logic, 2021 Less optimized natural lighting would result in apartment residents being dependent on artificial lighting, thus increasing energy consumption. Building opening orientation considerably influences the natural light intensity.
Aisyah Anindya Putri +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Alternatives in light and space: rethinking public lighting in shared spaces [PDF]
, 2011 This study reconsiders current public lighting design and suggests alternative practices that were determined through a case study involving a main street shopping strip.
Denis Smitka
core
Assessment of Interior and Area Artificial Lighting in Hospitals of Hamadan City
Muhandisī-i bihdāsht-i ḥirfah/ī, 2014 Background & Objectives: Comfort lighting is one of the most important topics, which provides optimum physical conditions in general environment and workplaces such as hospitals.
Rostam Golmohamadi +4 more
doaj
Journal of Architecture, Art & Humanistic Science, 2018 The absence of a study of the relationship between the subjective colors of the light source itself (industrial / natural light) and the reflective colors resulting from the elements of the interior design in the scene, and the relationship in the ...
Sawsan Amer, Sally Iraqi
doaj +1 more source