Results 41 to 50 of about 12,997 (305)

A picturesque interior space

Проект Байкал, 2022
The dwelling interior is an essential component of everyday happiness. One of the most ancient and effective means to achieve psychological comfort in the house is easel interior painting.
Наталия Ульянова
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Estudo comparativo de sistemas de iluminação artificial com diferentes luminárias considerando a disponibilidade de luz natural [PDF]

, 2012
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro Tecnológico, Programa de Pós-Graduação em Arquitetura e UrbanismoO aproveitamento da iluminação natural é indicado como um fator primordial na economia de energia das edificações ...
Moraes, Letícia Niero
core  

The effect of environmental control systems on the interior residential space and its users

Journal of Architecture, Art & Humanistic Science, 2021
Environmental control is currently one of the most important research topics because it has a great effect on the internal space and its residents especially and on the environment, architecture and urban design in general.
Asmaa Elsayed Lotfy Elkalla, Yasser Ali Mabed, Alaa Mohammed Shams-Eldeen El-Aishy   +2 more
doaj   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

Analyzing the Interior Levels of Natural Lighting in an Early Republican Era Building: An Example from the Laboratories of Ankara Refik Saydam Sanitation Institute Chemistry and Bacteriology Building [PDF]

Ankara Araştırmaları Dergisi, 2017
Having witnessed changes up to the present day in terms of aesthetics, function, sustainability, and user-space relationships, Ankara has come to prominence through its dynamic structure, and has become the subject of various debates.
Ayşe Nihan Avcı, İpek Memikoğlu
doaj   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Impact of Light Environment on Driver's Physiology and Psychology in Interior Zone of Long Tunnel

Frontiers in Public Health, 2022
In tunnels, lighting not only affects visual performance, but also non-visual aspects such as drivers' physiological fatigue and mental stress. The non-visual impacts in the interior zone of long tunnels are particularly prominent as drivers are confined
Li Peng, Ji Weng, Yi Yang, Huaiwei Wen
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Caracterização do zoneamento da iluminação natural e sua influência no controle da iluminação artficial [PDF]

, 2012
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro Tecnológico. Programa de Pós-Graduação em Arquitetura e Urbanismo.O uso da luz natural além de garantir níveis de iluminação adequados para as atividades humanas reduz a necessidade ...
Rocha, Ana Paula de Almeida
core