Results 121 to 130 of about 279,979 (283)

The role of inflammation in epilepsy. [PDF]

, 2011
Epilepsy is the third most common chronic brain disorder, and is characterized by an enduring predisposition to generate seizures. Despite progress in pharmacological and surgical treatments of epilepsy, relatively little is known about the processes ...
A Crespel, A Iyer, A Liesz, A Mantovani, A Mouihate, A Pitkanen, A Pitkanen, A Vezzani, A Vezzani, A Vezzani, A Vezzani, A Vezzani, A Vincent, A Vincent, AL Lux, AM Iyer, Annamaria Vezzani, AR Crow, AR Ferguson, AT Berg, B Lee, B Viviani, B Viviani, B Voutsinos-Porche, BD Semple, BJ Baker, BJ Kelley, BT Hawkins, C Chen, C Cunningham, C Dubé, C Dubé, C Eriksson, C Marescaux, CA Dinarello, CA Dinarello, CA Pardo, CG Bien, CG Bien, CG Bien, CH Khuu, CK Glass, CM Dubé, CM Dubé, CN Davis, CR Plata-Salaman, D Shlosberg, D Stellwagen, DB Sinclair, E Aronica, E Lahat, E Lloyd, E Oby, E Perucca, E Wirrell, EA van Vliet, EH Wilson, EM Harre, F Clausen, F Dhote, F Villani, G De Sarro, GC Blobe, H Samland, H Verhelst, HH Ho, I Rozovsky, IJ Elenkov, IL Campbell, IV Tabarean, J Choi, J Dalmau, J Marcon, JA Aarli, JA French, JA Gorter, Jacqueline French, JG Heida, JH Xu, JM Pellock, JS Duncan, JW Wheless, K Akassoglou, K Boer, K Boer, K Hoebe, K Lukasiuk, K Riazi, K Yoshikawa, KA Kelley, KA Slanina, KH Jung, KJ Tracey, KL Brunson, KL Brunson, KL van Gassen, L Holtman, L Librizzi, L Longhi, LA O'Neill, LP Cacheaux, M Joels, M Majores, M Maldonado, M Maroso, M Minami, M Rizzi, M Sanchez-Alavez, M Sayyah, M Schwartz, M Utech, M Virta, M Wirenfeldt, M Zetterstrom, MA Galic, MA Mikati, MA Mikati, MA Rogawski, MD Nguyen, MF Tsan, MG De Simoni, MH Scantlebury, ML Foresti, MT Mackay, N Marchi, N Polascheck, NC Manley, ND Perkins, NJ Rothwell, NP Turrin, P Bezzi, PF Fabene, PF Fabene, PS Buckmaster, R Dantzer, R Mantegazza, R Riikonen, R Sapolsky, R Watson, R Zhang, RM Ransohoff, S Akira, S Auvin, S Auvin, S Balosso, S Balosso, S Gatti, S Haspolat, S Hu, S Najjar, SE Baranzini, SH Appel, SJ You, SK Kulkarni, SM Allan, SM Allan, SM Gloor, SW Rogers, T Bartfai, T Bartfai, T Cartmell, T Cullingford, T Ichiyama, T Rasmussen, T Ravizza, T Ravizza, T Ravizza, T Ravizza, T Ravizza, T Ravizza, Tallie Z. Baram, Tamas Bartfai, TD Gilmore, TZ Baram, TZ Baram, WA Banks, Y David, Y Takahashi, Y Wu, Z Kovacs, Z Szekanecz, ZQ Xiong   +181 more
core   +1 more source

Paracrine Factor Local Gradient‐Generating System for Engineering Perfusable Vascularized Hepatocyte Tissues with Perfusion‐Induced Proliferation

Advanced Healthcare Materials, EarlyView.
A paracrine factor local gradient (PFLG)‐generating system enables microvessel penetration across 3D hepatocyte tissues. The resulting vascularized constructs recapitulate hepatic sinusoidal hepatocyte—endothelial contact architecture and enhance hepatic functions in vitro.
Yen‐Hsiang Huang, Tadahiro Yamashita, Ryo Sudo   +2 more
wiley   +1 more source

Advanced 3D Platforms for Modeling CNS Neuroinflammation: Cell Integration, Techniques, and Challenges

Advanced Healthcare Materials, EarlyView.
This review summarizes the roles of key central nervous system cell types, the extracellular matrix, and the blood‐brain barrier in neuroinflammation, and their integration into diverse 3D culture systems. It examines major incorporation strategies, including direct co‐culture, hydrogel encapsulation, transwell migration assays, and bioprinting ...
Emmanuelle D. Aiyegbusi, Julia Di Stefano, Dearbhaile Dooley   +2 more
wiley   +1 more source

Interleukin-1β expression on periodontitis patients in Surabaya

Dental Journal, 2010
Background: Periodontal disease, commonly known as periodontitis is an infectious disease which has multifactorial etiologic factors. It may affect everybody in any ages with no gender nor sex predilection and usually can be detected under routine ...
Chiquita Prahasanti
doaj   +1 more source

A Long‐Lived Human Neurovascular PENTA Culture Model Captures Incomplete Vascular Repair and Glia‐Associated Signaling After Traumatic Brain Injury

Advanced Healthcare Materials, EarlyView.
A long‐lived, five‐cell‐type human neurovascular (PENTA) model recreates vascular disorganization and incomplete repair after traumatic brain injury (TBI). By integrating endothelial, glial, neuronal, and immune components within a 3D scaffold, the platform enables time‐resolved analysis of neurovascular remodeling and provides a human‐relevant system ...
Daniel S. Hinrichsen, Sunghyun Jun, Colleen M. Arrasmith, Charitha C. Anamala, Mitchell D. Thielen, Anapaula Garcia, Volha Liaudanskaya   +6 more
wiley   +1 more source

Effects of Early Therapeutic Administration of Interleukin-1β on Survival Rate and Bone Marrow Hemopoiesis of Irradiated Mice

Acta Medica, 2010
The study was aimed at the experimental assessment of the efficacy of recombinant interleukin-1β in the early therapy of haemopoiesis disorders caused by X-ray irradiation.
Alexander Grebenyuk, Victor Zatsepin, Natalia Aksenova, Alexander Timoshevsky   +3 more
doaj   +1 more source

Macrophage Membrane‐Cloaked, ROS‐Triggered Quercetin Nanocarriers Target Ovarian Lesions to Treat Polycystic Ovary Syndrome

Advanced Healthcare Materials, EarlyView.
The synthesis process of MM@PCD@QNPs and its potential mechanism for treating PCOS. (A) Assembly steps of MM@PCD@QNPs. (B) Synthesis and decomposition of MM@PCD@QNPs. (C) Potential therapeutic mechanisms of MM@PCD@QNPs for PCOS. PCD, PABP conjugated with DEX polymer; QUR, quercetin; CDI, N, N′‐carbonyldiimidazole; DEX, dextran; PABP, 4‐(hydroxymethyl ...
Wenzhu Li, Yu Guan, Nan Song, Feng Zhang, Zhimin Deng, Tailang Yin, Yanbing Yang, João Conde, Wenyi Jin, Zhinang Yin   +9 more
wiley   +1 more source

FOXC1 restrains NF‐κB‐mediated interleukin‐1β transcription in breast cancer

MedComm, 2023
Yan Liu, Shuang Chen, Mao Tian, Armando Giuliano, Xiaojiang Cui   +4 more
doaj   +1 more source

Sprayable Polymer Blends With Short‐Chain Surface Segregation for Preventing Postoperative Abdominal Adhesions

Advanced Healthcare Materials, EarlyView.
Adhesions’ high occurrence rates and high morbidity render them a critical challenge to be addressed. Current prevention methods, such as physical barriers, have many limitations, resulting in inconsistent safety and efficacy. This study demonstrates the potential for sprayable polymeric materials as an adhesion barrier.
Robert J. Morris III, Tejaswi Nori, Alex I. Halpern, Hannah LaPadula, Arthur V. Cresce, Sarah L. Wright, Anthony D. Sandler, Peter Kofinas   +7 more
wiley   +1 more source

B14 ameliorates bone cancer pain through downregulating spinal interleukin-1β via suppressing neuron JAK2/STAT3 pathway

Molecular Pain, 2019
Curcumin has several pharmacological properties such as anti-inflammatory, antioxidant, and neuroprotective activities. B14 is a curcumin analogue and is considered to be a more potent compound with preserved pharmacodynamic activities.
Miao Xu, Huadong Ni, Longsheng Xu, Hui Shen, Housheng Deng, Yungong Wang, Ming Yao   +6 more
doaj   +1 more source