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Interleukin-1β induces trained innate immunity in human hematopoietic progenitor cells in vitro. [PDF]
Flores-Gomez D +10 more
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Tetrahydroxylated bile acids prevents malignant progression of Barret esophagus <i>in vitro</i> by inhibiting the interleukin-1β-nuclear factor kappa-B pathway. [PDF]
Mamchur A +8 more
europepmc +1 more source
Editorial: Targeting the interleukin-1β/interleukin-6/C-reactive protein pathway in clinical medicine - a road map to clinical trial design. [PDF]
Torzewski J +4 more
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Interleukin-1β Inhibits Glutamate Release in Hippocampus of Young, But Not Aged, Rats
Neurobiology of Aging, 1997The proinflammatory cytokine, interleukin-1, is synthesized in neuronal and glial cells and is released in response to stress/injury. IL-1 exerts profound effects on the central nervous system, which include an inhibitory effect on synaptic activity in hippocampus, a brain area expressing a high density of IL-1 receptors.
C A, Murray +3 more
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Neurobiology of Aging, 2001
Transgenic APPV717F mice, homozygous for a human minigene encoding the V717F familial Alzheimer's disease mutation, develop Abeta plaques similar to those seen in Alzheimer patients and show evidence of neuronal cell drop out in CA2-3 regions of the hippocampus at 8 months of age and older. Interleukin-1 (IL-1)beta (IL-1beta) converting enzyme (ICE) is
J G, Sheng +10 more
openaire +2 more sources
Transgenic APPV717F mice, homozygous for a human minigene encoding the V717F familial Alzheimer's disease mutation, develop Abeta plaques similar to those seen in Alzheimer patients and show evidence of neuronal cell drop out in CA2-3 regions of the hippocampus at 8 months of age and older. Interleukin-1 (IL-1)beta (IL-1beta) converting enzyme (ICE) is
J G, Sheng +10 more
openaire +2 more sources
Journal of Neuroimmunology, 1997
Systemic administration of endotoxin (LPS) or interleukin-1beta (IL-1) to prepubertal rats induced a marked increase in splenic but not cardiac norepinephrine (NE) turnover, an index of sympathetic neural activity. In contrast, the splenic neural response was blunted in their fetal alcohol-exposed (FAE) cohorts.
Z, Gottesfeld, S, Simpson, M, Maier
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Systemic administration of endotoxin (LPS) or interleukin-1beta (IL-1) to prepubertal rats induced a marked increase in splenic but not cardiac norepinephrine (NE) turnover, an index of sympathetic neural activity. In contrast, the splenic neural response was blunted in their fetal alcohol-exposed (FAE) cohorts.
Z, Gottesfeld, S, Simpson, M, Maier
openaire +2 more sources
Progress in Neurobiology, 1998
Ageing is associated with impairments in a variety of biological functions, one of the most striking might be considered to be the impairment in cognitive function. This impairment probably relates to the vulnerability of the hippocampus to the ageing process, since several cognitive functions rely on the integrity of this brain area.
openaire +2 more sources
Ageing is associated with impairments in a variety of biological functions, one of the most striking might be considered to be the impairment in cognitive function. This impairment probably relates to the vulnerability of the hippocampus to the ageing process, since several cognitive functions rely on the integrity of this brain area.
openaire +2 more sources

