Results 251 to 260 of about 516,739 (277)

Interleukin-1β Inhibits Glutamate Release in Hippocampus of Young, But Not Aged, Rats

Neurobiology of Aging, 1997
The proinflammatory cytokine, interleukin-1, is synthesized in neuronal and glial cells and is released in response to stress/injury. IL-1 exerts profound effects on the central nervous system, which include an inhibitory effect on synaptic activity in hippocampus, a brain area expressing a high density of IL-1 receptors.
C A, Murray, B, McGahon, S, McBennett, M A, Lynch   +3 more
openaire   +2 more sources

Neuronal DNA damage correlates with overexpression of interleukin-1β converting enzyme in APPV717F mice

Neurobiology of Aging, 2001
Transgenic APPV717F mice, homozygous for a human minigene encoding the V717F familial Alzheimer's disease mutation, develop Abeta plaques similar to those seen in Alzheimer patients and show evidence of neuronal cell drop out in CA2-3 regions of the hippocampus at 8 months of age and older. Interleukin-1 (IL-1)beta (IL-1beta) converting enzyme (ICE) is
J G, Sheng, R E, Mrak, R A, Jones, M M, Brewer, X Q, Zhou, J, McGinness, S, Woodward, K, Bales, S M, Paul, B, Cordell, W S, Griffin   +10 more
openaire   +2 more sources

Exposure to alcohol in utero blunts splenic sympathetic neural response to endotoxin and interleukin-1β in the rat

Journal of Neuroimmunology, 1997
Systemic administration of endotoxin (LPS) or interleukin-1beta (IL-1) to prepubertal rats induced a marked increase in splenic but not cardiac norepinephrine (NE) turnover, an index of sympathetic neural activity. In contrast, the splenic neural response was blunted in their fetal alcohol-exposed (FAE) cohorts.
Z, Gottesfeld, S, Simpson, M, Maier
openaire   +2 more sources

Age-related impairment in long-term potentiation in hippocampus: a role for the cytokine, interleukin-1β?

Progress in Neurobiology, 1998
Ageing is associated with impairments in a variety of biological functions, one of the most striking might be considered to be the impairment in cognitive function. This impairment probably relates to the vulnerability of the hippocampus to the ageing process, since several cognitive functions rely on the integrity of this brain area.
openaire   +2 more sources

Δ9-Tetrahydrocannabinol Inhibits Transforming Growth Factor Î'1 Induced Pro-Fibrotic and Nociceptive Gene Expression and Stimulates Interleukin 1Î' MRNA Expression in Human Intestinal Myofibroblasts

Gastroenterology, 2017
Christopher Broxson, Ellen M. Zimmermann
openaire   +1 more source

Interleukin-6 Signaling and Anti-Interleukin-6 Therapeutics in Cardiovascular Disease

Circulation Research, 2021

exaly  

Specific binding of systemically administrated radiolabeled interleukin-1α (IL-1α) to type II IL-1 receptor in focal inflammation in mice

Immunology Letters, 1997
openaire   +1 more source

Serum levels of interleukin-1β, interleukin-2 receptor, interleukin-6 and tumor necrosis factor-α levels in patient with chronic liver disease

Journal of Hepatology, 2001
openaire   +1 more source

Biology and therapeutic potential of interleukin-10

Journal of Experimental Medicine, 2020
Anne O'Garra, Margarida Saraiva, Paulo Vieira   +2 more
exaly  

Interleukin-22: Immunobiology and Pathology

Annual Review of Immunology, 2015
Jarrod Dudakov, Alan Hanash
exaly