Results 171 to 180 of about 441,802 (306)

Engineering Osteoimmune Responses with Functionalized Orthopedic Implants for Post‐Operative Osteosarcoma Treatment

open access: yesAdvanced Science, EarlyView.
Osteosarcoma is the most common primary bone tumor with limited treatment options and a terrible prognosis. This review provides a comprehensive summary of the recent development of osteoimmunomodulatory implants for post‐operative osteosarcoma treatment, of which the potential utility in evoking durable anti‐osteosarcoma immunity and accelerating bone
Yilong Dong   +6 more
wiley   +1 more source

Periodontal and peri-implant status and whole salivary interleukin 1-beta levels among individuals using selective serotonin reuptake inhibitors: an observational study. [PDF]

open access: yesBMC Oral Health, 2023
ALHarthi SS   +7 more
europepmc   +1 more source

Discovery of H2 Receptor Antagonists as Colistin Enhancers by Targeting Acid Stress Response

open access: yesAdvanced Science, EarlyView.
This study identifies YqgB as a key target for restoring colistin susceptibility in mcr‐positive pathogens under acidic conditions by remodeling phospholipid composition and reducing LPS modification. Deep learning‐based screening reveals H2 receptor antagonists as novel colistin adjuvants. Further investigations indicate that ranitidine and famotidine
Jinju Cai   +7 more
wiley   +1 more source

Diagnostic utility of circulating interleukin-1 beta and microRNA-146a in differentiating febrile seizures from other pediatric conditions. [PDF]

open access: yesWorld J Exp Med
Mohammadi S   +8 more
europepmc   +1 more source

Inulin‐Based Oral Chemotherapy Modulates Gut Microbiota and Immune Microenvironment through Inhibition of Neutrophil Extracellular Trap Formation for Improving Cancer Therapy

open access: yesAdvanced Science, EarlyView.
Schematic representation of ZIF‐8@OXA@inulin for cancer immunotherapy. Synthesis of ZIF‐8@OXA@inulin. Augmentation of pyroptosis, regulation of gut microbiota, and inhibition of NETs formation by ZIF‐8@OXA@inulin‐mediated comprehensive strategy for antitumor immune response. ABSTRACT Despite the potential of chemoimmunotherapy against colorectal cancer
Zhenhao Li   +8 more
wiley   +1 more source

Downregulation of interleukin-1 beta via Jmjd3 inhibition improves post-myocardial infarction depression. [PDF]

open access: yesCardiovasc Diagn Ther, 2022
Tang X   +9 more
europepmc   +1 more source

Cytokines and chemokines in Mycobacterium tuberculosis infection [PDF]

open access: yes, 2016
Cooper, Andrea   +3 more
core   +2 more sources

BGN/MDK Axis in the Melanoma Tumor Microenvironment Strengthens Tumor Malignancy by Modulating Cancer Cells and Cancer‐Associated Fibroblasts Crosstalk

open access: yesAdvanced Science, EarlyView.
This study reveals that m6A regulators cooperatively upregulate BGN in melanoma, promoting malignancy. Within the tumor microenvironment, CAFs show highest BGN expression. The BGN/MDK axis mediates cancer‐stroma crosstalk, driving normal fibroblast (NF) activation and enhancing the pro‐tumor effect of CAFs, highlighting a promising therapeutic target ...
Hao‐ze Shi   +16 more
wiley   +1 more source

Phenotypic Changes in a Monocyte Cluster with High Interleukin-1 Beta Expression during Long-Term Anti-CD20 Therapy. [PDF]

open access: yesAnn Neurol
Waede M   +10 more
europepmc   +1 more source

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