Results 181 to 190 of about 441,802 (306)

Anti-atherosclerotic effects of naringenin and quercetin from Folium Artemisiae argyi by attenuating Interleukin-1 beta (IL-1β)/ matrix metalloproteinase 9 (MMP9): network pharmacology-based analysis and validation. [PDF]

BMC Complement Med Ther, 2023
Zhang L, Yang Z, Li X, Hua Y, Fan G, He F.   +5 more
europepmc   +1 more source

Fibroblast Activation Protein Promotes Thoracic Aortic Dissection via PLAUR/ITGB1‐Mediated Pro‐inflammatory Macrophage Polarization

Advanced Science, EarlyView.
This study reveals that FAP promotes thoracic aortic dissection (TAD) through a nonenzymatic mechanism involving fibroblast‐macrophage crosstalk via the FAP/PLAUR/ITGB1/FAK axis. Targeting this pathway might offer a promising therapeutic strategy for TAD.
Hongqiao Zhu, Jianlie Wu, Ziyi Xu, Yifei Pei, Zaiping Jing, Jian Zhou, Rui Feng, Junjun Liu   +7 more
wiley   +1 more source

Molecular docking and MD simulations predicted quercetin as a potent human interleukin-1 beta (hIL1β) inhibitor for improved endodontic disease management. [PDF]

PLoS One
Boreak N, Almasoudi SA, Alharbi A, Judayba M, Tahrei S, Eishah AA, Madkhali TA, Hattan MA, Majrashi MH, Daak HA, Hakami A.   +10 more
europepmc   +1 more source

The association between serum interleukin-1 beta and heparin sulphate in diabetic nephropathy patients. [PDF]

Glycoconj J, 2021
Jiang L, Zhou J, Zhang L, Du Y, Jiang M, Xie L, Ma Z, Chen F.   +7 more
europepmc   +1 more source

Irgm1 Improves Postinfarction Cardiac Repair by Promoting Neutrophil Clearance and Efferocytosis

Advanced Science, EarlyView.
The Irgm1‐PDIA3 axis enhances post‐infarction cardiac repair by accelerating neutrophil clearance and facilitating efferocytosis. Irgm1 holds potential as a prognostic biomarker in MI, and LOC14 may represent a therapeutic option to improve cardiac repair, especially in cases of Irgm1 deficiency.
Zeng Wang, Lai Wei, Mingyang Wang, Shanjie Wang, Lili Xiu, Jiaxiang Sun, Rongzhe Lu, Yige Liu, Jiaxin Wang, Fengyi Liu, Weike Liu, Bo Yu, Yong Sun, Xueqin Gao, Shaohong Fang   +14 more
wiley   +1 more source

Inhibition of interleukin-1 receptor-associated kinase (IRAK)-4 provides partial rescue of interleukin-1 beta induced functional and gene expression changes in equine tenocytes. [PDF]

Mol Biol Rep
Beaumont RE, Flood C, Guest DJ.
europepmc   +1 more source

Effect of Green Tea on the Level of Salivary Interleukin-1 Beta in Patients with Chronic Periodontitis: A Randomized Clinical Trial. [PDF]

Int J Dent, 2022
Rezvani G, Taleghani F, Valizadeh M.
europepmc   +1 more source

Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy

Advanced Science, EarlyView.
Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong, Yuhang Xie, Zhijie Weng, Yongzhi Wu, Longjiang Li, Bo Li   +5 more
wiley   +1 more source

FL/FLT3 signaling enhances mechanical pain hypersensitivity through Interleukin-1 beta (IL-1β) in male mice. [PDF]

Neurobiol Pain
Sonrier C, Sar C, Melo I, Dioufoulet L, Lucena-Silva GV, Mallié S, Bertin J, Leyris JP, Ango F, Cunha TM, Ou Maati HM, Valmier J, Rivat C, Méchaly I.   +13 more
europepmc   +1 more source

Is the Success of Cefazolin plus Ertapenem in Methicillin-Susceptible Staphylococcus aureus Bacteremia Based on Release of Interleukin-1 Beta? [PDF]

Antimicrob Agents Chemother, 2022
Smelter D, Hayney M, Sakoulas G, Rose W.
europepmc   +1 more source