Results 301 to 310 of about 2,108,740 (316)

Association of serum interleukin‐33 level and the interleukin‐33 genetic variant with Japanese cedar pollinosis

Clinical & Experimental Allergy, 2008
SummaryBackground IL‐33, an IL‐1‐like cytokine, is a ligand for IL1RL1, which is an important effector molecule of type 2 T helper responses. Although IL‐33/IL1RL1 interaction has been suggested to be important in induction of allergic airway inflammation, serum levels of IL‐33 and the genetic influences of the polymorphisms of IL‐33 in human ...
M, Sakashita, T, Yoshimoto, T, Hirota, M, Harada, K, Okubo, Y, Osawa, S, Fujieda, Y, Nakamura, K, Yasuda, K, Nakanishi, M, Tamari   +10 more
openaire   +2 more sources

Interleukin-33 safeguards neutrophils in sepsis

Nature Medicine, 2010
Cytokines have a fundamental role in orchestrating innate immune responses to bacterial infections. Interleukin-33 (IL-33) is now shown to protect from sepsis by promoting neutrophil influx into the focus of infection (pages 708–712).
Thierry Roger, Thierry Calandra
openaire   +1 more source

Interleukin-33: a regulator of basophils

Blood, 2009
The cytokine network controlling basophils has been extended to interleukin-33. This commentary provides an update and summary on this emerging concept.
openaire   +2 more sources

IL-33, an interleukin-1-like cytokine that signals via the IL-1 receptor-related protein ST2 and induces T helper type 2-associated cytokines.

Immunity, 2005
Cytokines of the interleukin-1 (IL-1) family, such as IL-1 alpha/beta and IL-18, have important functions in host defense, immune regulation, and inflammation. Insight into their biological functions has led to novel therapeutic approaches to treat human
J. Schmitz, Alexander M. Owyang, E. Oldham, Yaoli Song, E. Murphy, T. Mcclanahan, G. Zurawski, M. Moshrefi, J. Qin, Xiaoxia Li, D. Gorman, J. Fernando Bazan, R. Kastelein, Schering-Plough Biopharma   +13 more
semanticscholar   +1 more source

Brain Foxp3+ regulatory T cells can be expanded by Interleukin-33 in mouse ischemic stroke.

International Immunopharmacology, 2019
BACKGROUND Regulatory T (Treg) cells are known as immune regulators to decrease infarct volume and improve outcomes after ischemic stroke. Thus, the strategies for increasing Treg cells in ischemic brain may have the beneficial effects on stroke. In this
Shuang Guo, Yi Luo
semanticscholar   +1 more source

Upregulation of Interleukin-33 in obstructive renal injury

Biochemical and Biophysical Research Communications, 2016
Interstitial fibrosis and loss of parenchymal tubular cells are the common outcomes of progressive renal diseases. Pro-inflammatory cytokines have been known contributing to the damage of tubular cells and fibrosis responses after renal injury. Interleukin (IL)-33 is a tissue-derived nucleus alarmin that drives inflammatory responses.
Wei-Yu Chen, Ya-Jen Chang, Chia-Hao Su, Tzu-Hsien Tsai, Shang-Der Chen, Chung-Hsi Hsing, Jenq-Lin Yang   +6 more
openaire   +2 more sources

Interleukin‐33 in the developing lung—Roles in asthma and infection

Pediatric Allergy and Immunology, 2019
It has become increasingly clear that interleukin‐33 (IL‐33) plays a crucial role in initiation of type 2 immunity. The last decade of intense research has uncovered multiple mechanisms through which IL‐33 targets key effector cells of the allergic ...
K. Johansson, H. McSorley
semanticscholar   +1 more source

Interleukin-33 reduces neuronal damage and white matter injury via selective microglia M2 polarization after intracerebral hemorrhage in rats.

Brain Research Bulletin, 2019
Interleukin-33 (IL-33) is closely related to the regulation of immunological cells, and its receptor ST2 is a member of the interleukin-1 (IL-1) receptor family.
Zhouqing Chen, Na Xu, Xuejiao Dai, Chongshun Zhao, Xin Wu, Sandhya Shankar, Huachen Huang, Zhong Wang   +7 more
semanticscholar   +1 more source

NMR assignments of the human cytokine interleukin-33

Biomolecular NMR Assignments, 2009
We report near complete NMR backbone and side chain assignments of the human cytokine interleukin-33 (IL-33) in solution. IL-33 is the latest addition to the family of interleukin-1 homologous cytokines and was shown to be involved in inflammation and autoimmune diseases.
Andreas, Lingel, Wayne J, Fairbrother
openaire   +2 more sources

Targeting interleukin-33 in rheumatoid arthritis

Rheumatology International, 2011
Chao, Rong, Wei, Hu, Fan-Rong, Wu, Fei-Hu, Chen   +3 more
openaire   +2 more sources