Results 201 to 210 of about 417,692 (230)

Interleukin-39 exacerbates concanavalin A-induced liver injury

Immunopharmacology and Immunotoxicology, 2021
Interleukin (IL)-39 is a novel member of IL-12 family and has been reported to play a pro-inflammatory role in lupus-like mice, but its function in concanavalin A (ConA)-induced liver injury is currently unclear.In this study, we investigated the effects of IL-39 expression in a mouse model of ConA induced-hepatitis.
Yan Li, Luping Gong, Linjie Weng, Xiuhe Pan, Chaobo Liu, Mingcai Li   +5 more
openaire   +2 more sources

Circulating interleukin-39 as a potential biomarker for rheumatoid arthritis diagnosis

Clinical Biochemistry, 2023
Imbalances in cytokine networks have been shown to be a possible cause of rheumatoid arthritis (RA). The interleukin (IL)-12 family is involved in the pathogenesis of autoimmune diseases including RA, while IL-39 is a newly discovered member of the IL-12 family, although its role in RA remains unclear. The purpose of the present study was to detect the
Lina, Ying, Luping, Gong, Sicen, Meng, Xiudi, Wu, Mingcai, Li, Yan, Li   +5 more
openaire   +2 more sources

Elevated serum interleukin-39 levels in patients with neuromyelitis optica spectrum disorders correlated with disease severity

Multiple Sclerosis and Related Disorders, 2020
Neuromyelitis optica spectrum disorders (NMOSD) is an inflammatory demyelinating autoimmune disorder in the central nervous system (CNS), which is mainly mediated by aquaporin 4 antibodies (AQP4-Ab). Interleukin (IL)-39 is a new pro-inflammatory cytokine which belongs to the IL-12 cytokine family.
Meng-Ge Yang, Suyan Tian, Qingxiang Zhang, Jinming Han, Caiyun Liu, Yang Zhou, Jie Zhu, Tao Jin   +7 more
openaire   +2 more sources

Detection of serum and tissue levels of interleukin 39 in psoriasis: a case control study

Acta Dermatovenerologica Alpina Pannonica et Adriatica
Psoriasis is a chronic immune-mediated disorder with a genetic component that primarily affects the skin and has potential systemic involvement. Advances in understanding the interaction between the innate and adaptive immune systems have facilitated improved disease management.This study included 25 patients with psoriasis and 20 healthy controls of ...
Mohammed, Hassan, Talal A, Abd El-Raheem, Olfat G, Shaker, Hagar Ali, Kamal, Sara M, Yaseen, Amira E, Soliman   +5 more
openaire   +2 more sources

Interleukins in Cancer: From Biology to Therapy

Nature Reviews Cancer, 2021
Peter Libby, Daria Briukhovetska, Stefan Endres   +2 more
exaly  

Interleukin-35 (IL-35) and Interleukin-39 (IL-39) in Rheumatoid Arthritis: Relation to Disease Activity

Egyptian Journal of Medical Microbiology
Sahar A. Mouhran, Amany A. Abdallah, Ola Mounir   +2 more
openaire   +1 more source