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Integrated Single-Cell Profiling Reveals TL1A as a Biomarker and Driver of Type 2 Inflammation via Macrophage-Dependent Immunoregulation in Asthma. [PDF]
Zhang J +11 more
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The role of JAK3 and TEC family kinases in vitiligo pathogenesis. [PDF]
Passeron T +7 more
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TRABD2A promotes osteogenic differentiation of human periodontal ligament stem cells by modulating TNF-α and IL-1β. [PDF]
Lu H +5 more
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Soluble gp130 is the natural inhibitor of soluble interleukin‐6 receptor transsignaling responses
European Journal of Biochemistry, 2001Signal transduction in response to interleukin‐6 (IL‐6) requires binding of the cytokine to its receptor (IL‐6R) and subsequent homodimerization of the signal transducer gp130. The complex of IL‐6 and soluble IL‐6R (sIL‐6R) triggers dimerization of gp130 and induces responses on cells that do not express membrane bound IL‐6R.
T, Jostock +8 more
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