Results 171 to 180 of about 441,815 (305)

Anakinra and related drugs targeting interleukin-1 in the treatment of cryopyrin- associated periodic syndromes

Open Access Rheumatology: Research and Reviews, 2014
Inessa Bachove,1 Christopher Chang2 1Cooper University Hospital, Children's Regional Hospital, Camden, NJ, USA; 2Division of Allergy and Immunology, Thomas Jefferson University, Wilmington, DE, USA Abstract: Anakinra is an interleukin (IL) receptor ...
Bachove I, Chang C
doaj  

Periodontal and peri-implant status and whole salivary interleukin 1-beta levels among individuals using selective serotonin reuptake inhibitors: an observational study. [PDF]

BMC Oral Health, 2023
ALHarthi SS, BinShabaib MS, Alwahibi A, Gamal S, Elashiry E, Almershed SE, Alkhamis HA, Anweigi L.   +7 more
europepmc   +1 more source

Discovery of H2 Receptor Antagonists as Colistin Enhancers by Targeting Acid Stress Response

Advanced Science, EarlyView.
This study identifies YqgB as a key target for restoring colistin susceptibility in mcr‐positive pathogens under acidic conditions by remodeling phospholipid composition and reducing LPS modification. Deep learning‐based screening reveals H2 receptor antagonists as novel colistin adjuvants. Further investigations indicate that ranitidine and famotidine
Jinju Cai, Mengping He, Jianya Luo, Shuang Zhou, Tengyue Zhang, Jianing Li, Zhiqiang Wang, Yuan Liu   +7 more
wiley   +1 more source

Diagnostic utility of circulating interleukin-1 beta and microRNA-146a in differentiating febrile seizures from other pediatric conditions. [PDF]

World J Exp Med
Mohammadi S, Abbood Hameed Ati M, Seyedhosseini FS, Zare Ebrahimabad M, Saeidi M, Hosseini SA, Darweesh M, Al-Harrasi A, Yazdani Y.   +8 more
europepmc   +1 more source

Inulin‐Based Oral Chemotherapy Modulates Gut Microbiota and Immune Microenvironment through Inhibition of Neutrophil Extracellular Trap Formation for Improving Cancer Therapy

Advanced Science, EarlyView.
Schematic representation of ZIF‐8@OXA@inulin for cancer immunotherapy. Synthesis of ZIF‐8@OXA@inulin. Augmentation of pyroptosis, regulation of gut microbiota, and inhibition of NETs formation by ZIF‐8@OXA@inulin‐mediated comprehensive strategy for antitumor immune response. ABSTRACT Despite the potential of chemoimmunotherapy against colorectal cancer
Zhenhao Li, Jiaqiang Jiang, Yuping Zhou, Xinyuan Mao, Haotian Wen, Zhian Chen, Yutong Wang, Cong Huang, Yanfeng Hu   +8 more
wiley   +1 more source

Downregulation of interleukin-1 beta via Jmjd3 inhibition improves post-myocardial infarction depression. [PDF]

Cardiovasc Diagn Ther, 2022
Tang X, Liu R, Zhang Y, Zhu L, Shi W, Shan Y, Wu S, Li Y, Liu G, Ma W.   +9 more
europepmc   +1 more source

Cytokines and chemokines in Mycobacterium tuberculosis infection [PDF]

, 2016
Cooper, Andrea, Domingo-Gonzalez, Racquel, Khader, Shabaana A, Prince, Oliver   +3 more
core   +2 more sources

BGN/MDK Axis in the Melanoma Tumor Microenvironment Strengthens Tumor Malignancy by Modulating Cancer Cells and Cancer‐Associated Fibroblasts Crosstalk

Advanced Science, EarlyView.
This study reveals that m6A regulators cooperatively upregulate BGN in melanoma, promoting malignancy. Within the tumor microenvironment, CAFs show highest BGN expression. The BGN/MDK axis mediates cancer‐stroma crosstalk, driving normal fibroblast (NF) activation and enhancing the pro‐tumor effect of CAFs, highlighting a promising therapeutic target ...
Hao‐ze Shi, Ming‐yang Wu, Jin‐quan Liu, Cuicui Tian, Li Ma, Xue‐mei Zhou, Ze‐Hao Sun, Zhi‐yong Xu, Run‐dong Zhang, Shan‐yuan Ye, Li‐ming Huang, Yan Wang, Jing‐shu Xiong, Wen‐bo Bu, Xian‐feng Cheng, Jian‐fang Sun, Hao Chen   +16 more
wiley   +1 more source

Phenotypic Changes in a Monocyte Cluster with High Interleukin-1 Beta Expression during Long-Term Anti-CD20 Therapy. [PDF]

Ann Neurol
Waede M, Kingo C, Damsbo K, Joergensen MU, Oubounyt M, Gjerstorff M, Thomassen M, Baumbach J, Moeller JB, Elkjaer ML, Illes Z.   +10 more
europepmc   +1 more source

Anti-atherosclerotic effects of naringenin and quercetin from Folium Artemisiae argyi by attenuating Interleukin-1 beta (IL-1β)/ matrix metalloproteinase 9 (MMP9): network pharmacology-based analysis and validation. [PDF]

BMC Complement Med Ther, 2023
Zhang L, Yang Z, Li X, Hua Y, Fan G, He F.   +5 more
europepmc   +1 more source