Results 81 to 90 of about 441,815 (305)

The effects of tumor necrosis factor and interleukin 1 on osseous and soft tissue wound healing [PDF]

, 2002
Thesis (M.S.D.)--Boston University, Henry M. Goldman School of Dental Medicine, 2002 (Endodontics).Includes bibliography (leaves 63-68).The role of inflammatory mediators in surgical repair has not been delineated.
Gillen, Thomas
core  

Real‐World Investigation of Satralizumab in Patients With Neuromyelitis Optica Spectrum Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Satralizumab, a monoclonal antibody targeting the interleukin‐6 receptor, has demonstrated efficacy in clinical trials for neuromyelitis optica spectrum disorder (NMOSD). However, its real‐world effectiveness and safety compared to conventional immunosuppressive therapies remain uncertain.
Li‐Tsung Lin, Hui‐An Lin, Sheng‐Feng Lin   +2 more
wiley   +1 more source

Olink Proteomics Analysis Reveals Heterogeneous Responses to FcRn Blockade in Anti‐AChR Antibody‐Positive Myasthenia Gravis: FGF‐19 as a Novel Biomarker

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aimed to systematically observe the clinical manifestations, immune cell subsets, and dynamic changes in serological indicators in patients with myasthenia gravis (MG) before and after efgartigimod (EFG) treatment. Methods We analyzed the baseline data, laboratory parameters, and lymphocyte subset proportions in MG ...
Tiancheng Luo, Deyou Peng, Zhouao Zhang, Mingjin Yang, Xinyan Guo, Tianyu Ma, Xiaoyu Huang, Mingming Xu, Linlin Fu, Yong Zhang   +9 more
wiley   +1 more source

Tumor necrosis factor-alpha and interleukin-1 beta levels in children with bacterial, tuberculous and aseptic meningitis

The Turkish Journal of Pediatrics, 1997
Cerebrospinal fluid levels of tumor necrosis factor-alpha and interleukin-1 beta in 78 children with nonbacterial, bacterial and tuberculous meningitis, and in 34 control subjects were analyzed in order to evaluate the involvement of these ...
M Ceyhan, G Kanra, Z Ecevit, G Seçmeer, G Erdem, O Akan, O Müftüoğlu   +6 more
doaj  

Induction of Synovitis Using Interleukin-1 Beta: Are There Differences in the Response of Middle Carpal Joint Compared to the Tibiotarsal Joint?

Frontiers in Veterinary Science, 2018
Background: The effects of recombinant interleukin-1β (rIL-1β) have been described for the middle carpal joint (MCJ). However, we are unaware of any studies that have described the cytological response of the tibiotarsal joint (TTJ) to rIL-1β or compared
Aimee C. Colbath, Aimee C. Colbath, Steven W. Dow, Leone S. Hopkins, Jennifer N. Phillips, Jennifer N. Phillips, C. Wayne McIlwraith, C. Wayne McIlwraith, Laurie R. Goodrich, Laurie R. Goodrich   +9 more
doaj   +1 more source

THE CHANGES IN THE LEVEL OF BETA ENDORPHIN, INTERSLEUKIN-2, INTERLEUKIN-4, INTERLEUKIN-6, IMUNOGLOBULIN AND CORTISOL HORMONE ON THE PRACTICES OF SATRIA NUSANTARA [PDF]

, 2010
The purpose of this research is to reveal the changes of immunity at breathing exercises. This is an experimental research study. This research used “randomized pretest-posttest control group design.
Sudarko, Rumpis Agus
core  

Progress in spondylarthritis immunopathogenesis of spondyloarthritis: which cells drive disease? [PDF]

, 2009
Spondyloarthritides, or SpA, form a cluster of chronic inflammatory diseases with the axial skeleton as the most typical disease localisation, although extra-articular manifestations such as intestinal inflammation may frequently occur during the course ...
Melis, Lode, Elewaut, Dirk
core   +2 more sources

Immune‐Driven Expression in Inclusion Body Myositis With T‐Cell Large Granular Lymphocytic Leukemia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives T‐cell large granular lymphocytic leukemia (T‐LGLL), reported in up to 58% of inclusion body myositis (IBM) patients, is a rare leukemia of cytotoxic or less commonly helper T cells. The range of myopathies in T‐LGLL and the impact of coexisting T‐LGLL in IBM are not well understood. Our objectives are to investigate the spectrum of
Pannathat Soontrapa, Iago Pinal‐Fernandez, Pritikanta Paul, Michael P. Skolka, Margherita Milone, Min Shi, Mithun V. Shah, Maria Casal‐Dominguez, Katherine Pak, Andrew L. Mammen, Teerin Liewluck   +10 more
wiley   +1 more source

A subcutaneous adipose tissue-liver signalling axis controls hepatic gluconeogenesis. [PDF]

, 2015
The search for effective treatments for obesity and its comorbidities is of prime importance. We previously identified IKK-ε and TBK1 as promising therapeutic targets for the treatment of obesity and associated insulin resistance. Here we show that acute
Ahmadian, Maryam, Chang, Louise, Downes, Michael, Evans, Ronald M, Korytnaya, Evgenia, Krause, Danielle M, Liddle, Christopher, Lumeng, Carey N, Neidert, Adam, Oral, Elif A, Peng, Xiaoling, Poirier, BreAnne, Reilly, Shannon M, Saltiel, Alan R, Uhm, Maeran, Yu, Ruth T, Zamarron, Brian F   +16 more
core   +2 more sources

Immunohistochemical Localization of Interleukin-1.ALPHA., Interleukin-1.BETA. and Interleukin-6 in Human Gingival Tissue.

Nihon Shishubyo Gakkai Kaishi (Journal of the Japanese Society of Periodontology), 1994
炎症に関与するインターロイキン (IL) であるIL1α, IL1β およびIL6のヒト炎症歯肉組織における局在状況を解明するために, ヒト炎症歯肉組織について抗ヒトIL1α. IL1β ・IL6抗体を用いた免疫組織化学的検索を行った。その結果, IL1α の局在は, 歯肉内縁側, すなわちポケット上皮または口腔歯肉溝上皮, および接合上皮と, それら上皮下の結合組織に浸潤する好中球・マクロファージに見いだされた。IL1β もIL1α とほぼ同様の局在を示した。なお, 上皮と上皮下の炎症細胞では各IL1の陽性反応強度にそれぞれ違いが認められ, IL1α は上皮に, IL1β は炎症細胞により強い反応を呈した。IL6染色では, IL1陽性部位に加え ...
Hiroshi ITO, Takashi TAKATA, Mutsumi MIYAUCHI, Ikuko OGAWA, Hiromasa NIKAI   +4 more
openaire   +2 more sources