Results 111 to 120 of about 387,713 (336)
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
50 Years of Research in Real Estate Brokerage: A Semi-Systematic Literature Review
Real EstateIntermediaries are central to complex transactions. In housing markets, real estate brokers coordinate information flows, reduce search costs, and guide lay buyers and sellers through legal and financial steps.
Martin Ahlenius +2 more
doaj +1 more source
Mechanisms of parasite‐mediated disruption of brain vessels
FEBS Letters, EarlyView.Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
Los intérpretes generales de Yucatán: hombres entre dos mundos
Estudios de Cultura Maya, 2009 Este artículo se centra en un tipo importante de intermediarios en el Yucatán colonial, los intérpretes generales del Juzgado Privado de Indios de Yucatán.
Mark Lentz
doaj
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
International Arthouse Film Sales in the Face of the Rise of Video on Demand Platforms and Festivals
Biens SymboliquesSince the 1980s, the sale of international film rights has undergone a form of professionalization and normalization that is reflected in the consolidation of the profession of sales agent, which plays a key role in the globalization of independent ...
Ana Vinuela
doaj +1 more source
Competition between market-making Intermediaries [PDF]
We introduce capacity constrained competition between market-making intermediaries in a model in which agents can choose between trading with intermediaries, joining a search market or remaining inactive.
Simon Loertscher
core
Transact taxes in a price maker/taker market [PDF]
, 2012 We develop a price maker/taker model to study how a financial transaction tax affects markets. We find taxes widen quoted and effective spreads by more than twice the tax. Taxes increase volatility slightly (without intermediation) to significantly (with
Rosenthal, Dale W.R. +1 more
core +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Regulatory reform : integrating paradigms [PDF]
The Subprime crisis largely resulted from failures to internalize systemic risk evenly across financial intermediaries and recognize the implications of Knightian uncertainty and mood swings.
de la Torre, Augusto, Ize, Alain
core