Results 91 to 100 of about 57,834 (304)
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Non-competing data intermediaries
, 2020 I study a model of competing data intermediaries (e.g., online platforms and data brokers) that collect personal data from consumers and sell it to downstream firms.
Ichihashi, Shota
core +1 more source
Éditorial : Mieux rendre compte des figures des intermédiaires
Revue Européenne des Migrations Internationales, 2023 Olivier Clochard +2 more
doaj +1 more source
The future eTourism intermediaries
Tourism Management, 2002 Hitherto, the travel distribution role has been performed by traditional outgoing travel agents, tour operators and incoming travel agencies. They were supported by computer reservation systems, Global Distribution Systems (GDSs) or tour operators’ videotext systems (or leisure travel networks). These traditional electronic intermediaries (eMediaries),
Buhalis, Dimitrios +1 more
openaire +4 more sources
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Trade credit: why do production firms act as financial intermediaries? [PDF]
Trade credit remains the single largest source of short-term business credit in the United States and other nations around the world. Why do production firms act as financial intermediaries - a role usually reserved for banks?
Mitchell Berlin
core
Biens SymboliquesThis article examines the process of professionalization and autonomization of translation in the field of humanities and social sciences (HSS). This contribution is the result of a qualitative study based on interviews with professional translators ...
Lison Burlat
doaj +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Beyond knowledge brokerage: An exploratory study of innovation intermediaries in an evolving smallholder agricultural system in Kenya [PDF]
The recognition that innovation occurs in networks of heterogeneous actors and requires broad systemic support beyond knowledge brokering has resulted in a changing landscape of the intermediary domain in an increasingly market-driven agricultural sector
Klerkx, Laurens +3 more
core
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source