Results 111 to 120 of about 80,350 (298)

Considerations Regarding the Conclusion of the Insurance Contract by Electronic Means, Remotely, and Through Intermediaries

open access: yesCECCAR Business Review
Companies, insurance companies respectively, are moving their businesses online. Against this background, employees and management carry out their activity from home, travelling is avoided, gaining time for both contracting parties, and the activity ...
Ioana Nely MILITARU
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

The Impact of Financial Intermediaries on Resource Allocation and Economic Growth [PDF]

open access: yes
This paper examines the links between economic growth and the nature of a country’s financial system. It is argued that long-run growth has its roots in resource accumulation, and in particular in knowledge accumulation.
Philip Lowe
core  

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

How innovation intermediaries are shaping the technology market? An analysis of their business model [PDF]

open access: yes
In an era with abundant and widely distributed knowledge across the globe, technology markets became prominent. As technology transactions suffer from several market imperfections, a rapidly increasing number of various innovation intermediaries are ...
Vanhaverbeke, Wim, Lopez, Henry
core  

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

Intermediaries in sustainability transitions – differences and similarities of relevance for policy

open access: yes, 2017
Sustainability transitions require changes in existing socio-technological systems. Authors have underlined the relevance of intermediaries in the design and implementation of policies intended to facilitate sustainability transition.
Kanda, Wisdom,, Mignon, Ingrid,
core  

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

When is Seller Price Setting with Linear Fees Optimal for Intermediaries? [PDF]

open access: yes
Mechanisms where sellers set the price and are charged a linear commission fee are widely used by real world intermediaries, e.g. by real estate brokers. Empiri- cally these commission fees exhibit very little variance, both across heterogeneous regional
Simon Loertscher, Andras Niedermayer
core   +2 more sources

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