Results 131 to 140 of about 387,713 (336)

Financial Innovation and Financial Fragility [PDF]

open access: yes
We present a standard model of financial innovation, in which intermediaries engineer securities with cash flows that investors seek, but modify two assumptions. First, investors (and possibly intermediaries) neglect certain unlikely risks.
Andrei Shleifer   +2 more
core  

Blog symposium 'Strasbourg Observers turns ten' (2) : the Court’s subtle approach of online media platforms’ liability for user-generated content since the ‘Delfi Oracle’ [PDF]

open access: yes, 2020
This blog post, nearly five years after the final Delfi judgment (ECtHR Grand Chamber 16 June 2015), focusses on the impact of the Delfi case and gives a short overview of the further developments in the Court’s case law determining the scope of ...
Voorhoof, Dirk
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Cross-Border Printing Privileges in the Seventeenth-Century Low Countries

open access: yesEarly Modern Low Countries
Based on the assumption that printing privileges were meant to protect printer-publishers from market competition locally, scholars have primarily studied such privileges in individual states.
Nina Lamal
doaj   +1 more source

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

Social Media Companies' Cyberbullying Policies

open access: yesInternational Journal of Communication, 2016
This article examines social media companies’ responsibility in addressing cyberbullying among children. Through an analysis of companies’ bullying policies and mechanisms that they develop to address bullying, I examine the available evidence of the ...
Tijana Milosevic
doaj  

Financial Intermediation [PDF]

open access: yes
The savings/investment process in capitalist economies is organized around financial intermediation, making them a central institution of economic growth. Financial intermediaries are firms that borrow from consumer/savers and lend to companies that need
Andrew Winton, Gary Gorton
core  

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Considerations Regarding the Conclusion of the Insurance Contract by Electronic Means, Remotely, and Through Intermediaries

open access: yesCECCAR Business Review
Companies, insurance companies respectively, are moving their businesses online. Against this background, employees and management carry out their activity from home, travelling is avoided, gaining time for both contracting parties, and the activity ...
Ioana Nely MILITARU
doaj   +1 more source

Retirement saving and attitude towards financial intermediaries – Evidence for Germany [PDF]

open access: yes
People often disregard the need for individual savings for old-age although a decreasing rate of birth and an increasing life expectancy make it necessary to save additional money for retirement by using private or occupational pensions. Due to a lack of
Kathrin Dummann
core  

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