Results 131 to 140 of about 496,613 (305)
AAA+ protein unfoldases—the Moirai of the proteome
FEBS Letters, EarlyView.AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
Law, Finance and Investment: does legal origin matter? [PDF]
This paper assesses if legal origin explains domestic, foreign, private and public investments through financial intermediary channels of depth, efficiency, activity and size.
Simplice A., Asongu
core +1 more source
Intermediary Bodies in UK Higher Education Governance, with particular reference to Universities UK [PDF]
, 2007 This key note paper offers critical reflections on the role, functions, problems and challenges of intermediary bodies in the United Kingdom, and particularly those of Universities UK, which represents the heads of most HEIs.
Locke, William
core
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Potassium food supplement [PDF]
, 1973 Potassium gluconate is considered best supplementary source for potassium. Gluconate consistently received highest taste rating and was indistinguishable from nonsupplemented samples.
Bourland, C. T. +3 more
core +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
ДИВЕРСИФІКАЦІЯ МОДЕЛЕЙ ПОСЕРЕДНИЦТВА НА ГЛОБАЛЬНОМУ РИНКУ ПРОДОВОЛЬСТВА
International Journal of Innovative Technologies in Economy, 2018 The article researches intermediation models on the global food market using explicative method. The author proposes to diversify intermediation models on the basis of provided classification by thirteen criteria.
Рубан Т. С.
doaj
Bragging Through an Intermediary [PDF]
, 2017 The use of an intermediary to convey positive information about a target person is received more favorably and is more effective than direct self -promotion by the target person . These effects persist irrespective of whether the intermediary is motivated by self-interest . However, intermediation may carry image costs for the intermediary.
Scopelliti, Irene +2 more
openaire +2 more sources