Results 131 to 140 of about 160,868 (310)

The cortical actin cytoskeleton and desmosomes act together in keratin filament network maintenance

open access: yesEuropean Journal of Cell Biology
Keratin intermediate filaments are hallmark features of epithelial tissue differentiation forming complex cytoplasmic networks that are connected to subplasmalemmal cortical keratin filaments and anchored at desmosomal junctions.
Nicole Schwarz   +2 more
doaj   +1 more source

3D Multicellular Scaffold Based Model for Advancing Bone Disorder Research

open access: yesAdvanced Functional Materials, EarlyView.
A scalable 3D multicellular in vitro bone model engineered by integrating osteoblasts, osteoclasts, and endothelial cells on biodegradable scaffolds. The system recapitulates key features of human bone remodeling and disease pathology. As a proof of concept, the model mimics osteogenesis imperfecta, demonstrating its potential as a physiologically ...
Gali Guterman‐Ram   +5 more
wiley   +1 more source

The mechanical response of semiflexible networks to localized perturbations

open access: yes, 2005
Previous research on semiflexible polymers including cytoskeletal networks in cells has suggested the existence of distinct regimes of elastic response, in which the strain field is either uniform (affine) or non-uniform (non-affine) under external ...
A. J. Levine   +7 more
core   +2 more sources

Substrate Stress Relaxation Regulates Cell‐Mediated Assembly of Extracellular Matrix

open access: yesAdvanced Functional Materials, EarlyView.
Silicone‐based viscoelastic substrates with tunable stress relaxation reveal how matrix mechanics regulates cellular mechanosensing and cell‐mediated matrix remodelling in the stiff regime. High stress relaxation promotes assembly of fibronectin fibril‐like structures, increased nuclear localization of YAP and formation of β1 integrin‐enriched ...
Jonah L. Voigt   +2 more
wiley   +1 more source

Influence of microfluidic shear on keratin networks in living cells

open access: yesNew Journal of Physics, 2013
Intermediate filaments play a key role in cell mechanics, providing cells with compliance to small deformations and reinforcing them when large forces are applied.
Jens-Friedrich Nolting, Sarah Köster
doaj   +1 more source

Mechanically Tunable Bone Scaffolds: In Vivo Hardening of 3D‐Printed Calcium Phosphate/Polycaprolactone Inks

open access: yesAdvanced Functional Materials, EarlyView.
A 3D bone scaffold with osteogenic properties and capable of hardening in vivo is developed. The scaffold is implanted in a ductile state, and a phase transformation of the ceramic induces the stiffening and strengthening of the scaffold in vivo. Abstract Calcium phosphate 3D printing has revolutionized customized bone grafting.
Miguel Mateu‐Sanz   +7 more
wiley   +1 more source

Intermediate Filaments

open access: yesCold Spring Harbor Symposia on Quantitative Biology, 1982
M, Osborn   +4 more
openaire   +2 more sources

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