Results 71 to 80 of about 3,959,588 (324)

Broad Host Range of SARS-CoV-2 Predicted by Comparative and Structural Analysis of ACE2 in Vertebrates

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2020
Significance The novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the cause of COVID-19, a major pandemic that threatens millions of human lives and the global economy.
J. Damas   +18 more
semanticscholar   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Potential Intermediate Hosts for Coronavirus Transmission: No Evidence of Clade 2c Coronaviruses in Domestic Livestock from Ghana

open access: yesTropical Medicine and Infectious Disease, 2019
The emergence of Middle East Respiratory Syndrome Coronavirus (MERS-CoV), nearly a decade ago with worldwide distribution, was believed to be of zoonotic origin from bats with dromedary camels as intermediate hosts.
Philip El-Duah   +11 more
doaj   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Interactions of Equine Viruses with the Host Kinase Machinery and Implications for One Health and Human Disease

open access: yesViruses, 2023
Zoonotic pathogens that are vector-transmitted have and continue to contribute to several emerging infections globally. In recent years, spillover events of such zoonotic pathogens have increased in frequency as a result of direct contact with livestock,
Carol Anderson   +5 more
doaj   +1 more source

Orbital Evolution of Planets around Intermediate-Mass Giants

open access: yes, 2011
Around low- and intermediate-mass (1.5-3 M_sun) red giants, no planets have been found inside 0.6 AU. Such a paucity is not seen in the case of 1 M_sun main sequence stars. In this study, we examine the possibility that short-period planets were engulfed
Ida, S.   +4 more
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Metacercárias livres (Digenea: Diplostomidae) em Rhinella fernandezae (Anura: Bufonidae) no Sul do Brasil Free metacercariae (Digenea, Diplostomidae) in Rhinella fernandezae (Anura: Bufonidae) in southern Brazil

open access: yesCiência Rural, 2009
Metacercárias livres de uma espécie não determinada de trematódeo digenético (Diplostomidae) foram encontradas nos rins de anuros da espécie Rhinella fernandezae coletados no Município de Imbé, Litoral Norte do Rio Grande do Sul, Brasil.
Viviane Gularte Tavares dos Santos   +1 more
doaj  

Nonhost resistance to rust pathogens – a continuation of continua

open access: yesFrontiers in Plant Science, 2014
The rust fungi (order: Pucciniales) are a group of widely distributed fungal plant pathogens, which can infect representatives of all vascular plant groups.
Jan eBettgenhaeuser   +3 more
doaj   +1 more source

The shapes, orientation, and alignment of Galactic dark matter subhalos

open access: yes, 2007
We present a study of the shapes, orientations, and alignments of Galactic dark matter subhalos in the ``Via Lactea'' simulation of a Milky Way-size LCDM host halo.
Ciotti L.   +6 more
core   +1 more source

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