Results 101 to 110 of about 789,942 (260)
FEBS Letters, EarlyView.Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara +3 more
wiley +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
α‐Synuclein aggregation landscape from phase separation to neurotoxic intermediates
FEBS Letters, EarlyView.Alpha‐synuclein aggregation in Parkinson's disease involves a complex landscape of transient intermediates, including oligomers, fibrils and liquid–liquid phase separation (LLPS). A view is emerging in which LLPS maturation into solid‐like condensates may contribute to the formation of neurotoxic species.
Silvia Arino +2 more
wiley +1 more source
Intermediate modular curves with infinitely many quartic points
International Journal of Number TheoryFor every group [Formula: see text], there exists an intermediate modular curve [Formula: see text]. In this paper, we determine all curves [Formula: see text] with infinitely many points of degree 4 over [Formula: see text]. To do that, we developed a method to compute possible degrees of rational morphisms from [Formula: see text] to an elliptic ...
Maarten Derickx, Petar Orlić
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FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Meikuang AnquanIn order to investigate the effect of intermediate principal stress on the progressive damage and permeability characteristics of unloading sandstone, the unloading test was carried out under different intermediate principal stress conditions based on a ...
Jiahui DU +4 more
doaj +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Vocabulary Levels Test and Word Associates Test: Can they Measure Language Proficiency?
Asian Journal of Assessment in Teaching and Learning, 2016 The present study investigates whether it may be possible to use Vocabulary Levels Test (VLT) and Word Associates Test (WAT) for measuring language proficiency and placement purposes.
Mostafa Janebi Enayat +1 more
doaj
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Concerning the intermediate point in the mean value theorem [PDF]
Mathematical Inequalities & Applications, 2009 Dorel I. Duca, Ovidiu T. Pop
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