Results 101 to 110 of about 279,479 (299)

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Material for the intermediate python SIB-training course

open access: yes
<p>Course material for the 16-17 May 2024 edition of the two "Intermediate python" SIB courses:</p> <ul> <li>Data analysis and representation in python (course 1).</li> <li>Optimizing Python Code for Better ...
Robin Engler, Wandrille Duchemin
core   +1 more source

Enhancing source-based clone detection using intermediate representation [PDF]

open access: yes, 2010
-Detecting software clones in large scale projects helps improve the maintainability of large code bases. The source code representation (e.g., Java or C files) of a software system has traditionally been used for clone detection.
King Chun Foo, Ying Zou, Gehan M K Selim
core  

Intermediate Field Representation for Positive Matrix and Tensor Interactions

open access: yes, 2019
International audienceIn this paper we introduce an intermediate field representation for random matrices and random tensors with positive (stable) interactions of degree higher than 4.
Lionni, Luca, Rivasseau, Vincent
core   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Firm—a graph-based intermediate representation

open access: yes, 2011
We present our compiler intermediate representation FIRM. Pro-grams are always in SSA-form enabling a concise graph-based rep-resentation. We argue that this naturally encodes context informa-tion simplifying many analyses and optimizations. Instructions
Buchwald, Sebastian   +5 more
core   +1 more source

Biophysical approaches for studying viral entry

open access: yesFEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

Formalizing the LLVM Intermediate Representation for Verified Program Transformations

open access: yes, 2012
This paper presents Vellvm (verified LLVM), a framework for reasoning about programs expressed in LLVM\u27s intermediate representation and transformations that operate on it.
Steve Zdancewic   +7 more
core   +1 more source

PRESENCE AND RePRESENTATION [PDF]

open access: yes, 2012
The act of representation is, to an extent, a sine qua non condition within the artistic process andalways acquires its meaning in relation to a presence.
Giannaroudis, Konstantinos
core   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

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