Results 91 to 100 of about 7,666,987 (279)
Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells
FEBS Open Bio, EarlyView.Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim +4 more
wiley +1 more source
Determining the effect of strain rate on the fracture of sheet steel [PDF]
A key challenge for the automotive industry is to reduce vehicle mass without compromising on crash safety. To achieve this, it is necessary to model local failure in a material rather than design to the overly conservative criteria of total elongation
Beaumont, Richard Adrian
core
Pathways and pitfalls: a qualitative study of student experiences in biomedical science education
FEBS Open Bio, EarlyView.Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell +8 more
wiley +1 more source
NanomaterialsUnderstanding plastic deformation behaviour is key to optimising the mechanical properties of nano-polycrystalline layered composites. This study employs the molecular dynamics (MD) simulation to comprehensively investigate the effects of various factors,
Zhou Li +6 more
doaj +1 more source
Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface
FEBS Open Bio, EarlyView.HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana +5 more
wiley +1 more source
FEBS Open Bio, EarlyView.Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo +4 more
wiley +1 more source
EPJ Web of Conferences, 2012 Time-temperature equivalence is a widely recognized property of many time-dependent material systems, where there is a clear predictive link relating the deformation response at a nominal temperature and a high strain-rate to an equivalent response at a ...
Gray G.T. +4 more
doaj +1 more source
Delivery of DNA‐encoded vaccines and proteins in mice using cutaneous suction‐mediated transfection
FEBS Open Bio, EarlyView.Cutaneous suction‐mediated transfection in mice for delivery of DNA‐encoded vaccines and proteins. A critical limitation of DNA vaccines and other therapeutics is transfection in vivo to produce the encoded antigens or therapeutic proteins. Cutaneous suction‐based methods have demonstrated effectiveness in many animal models and have been successfully ...
Emran O. Lallow +12 more
wiley +1 more source
High strain-rate compressive behavior and constitutive modeling of selected polymers
EPJ Web of Conferences, 2012 The present paper deals with constitutive modeling of the compressive stress-strain behavior of selected polymers at strain rates from 10−3 to 103/s using a modified Ramberg-Osgood equation.
Yokoyama T., Nakai K.
doaj +1 more source
On the structural behavior of ship's shell structures due to impact loading
International Journal of Naval Architecture and Ocean Engineering, 2018 When collision accident between ships or between ship and offshore platform occurs, a common phenomenon that occurs in structures is the plastic deformation accompanied by a large strain such as fracture.
Hyung Kyun Lim, Joo-Sung Lee
doaj +1 more source