Results 81 to 90 of about 7,666,987 (279)
Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy
Molecular Oncology, EarlyView.LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Enterotoxigenic Bacteroides fragilis is a gut bacterium linked to bowel cancer. We propose that its toxin acts along two routes: at the cell surface, cutting the adhesion protein E‐cadherin and triggering inflammation; and inside the cell, delivered by bacterial vesicles, switching on NOD1 and cancer stem cell programs.
Kangchan Choi +2 more
wiley +1 more source
On the Rate Sensitivity of Coal
Engineering Transactions, 1983 This рареr describes the development of quasi-static and dynamic techniques applicable to compression testing of coal over a strain rate range of (…).
J.R. Klepaczko
doaj
The Self-Organized Critical Behavior in Pd-based Bulk Metallic Glass
Metals, 2015 Bulk metallic glasses (BMGs) deform irreversibly through shear banding manifested as serrated-flow behavior during compressive tests. The strain-rate-dependent plasticity under uniaxial compression at the strain rates of 2 × 10−2, 2 × 10−3, and 2 × 10−4 ...
Zhong Wang +4 more
doaj +1 more source
FEBS Open Bio, EarlyView.TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose +9 more
wiley +1 more source
MetalsThe present study focuses on the mechanical behaviour and formability of the aluminium alloy 2024-T3 in sheet form with a thickness of 0.8 mm. For this purpose, tensile tests at quasi-static and intermediate strain rates were performed using a universal ...
Martin Harant +3 more
doaj +1 more source
Recent developments in dynamic testing of materials
EPJ Web of Conferences, 2012 Three new testing configurations that have been developed since the last DYMAT conference in 2009 are presented. The first is high strain rate testing of Kevlar cloth and Kevlar yarn in a tensile Split Hopkinson Bar (SHB) apparatus. The Kevlar cloth/yarn
Seidt J.D., Gilat A.
doaj +1 more source
Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes
FEBS Open Bio, EarlyView.Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard +12 more
wiley +1 more source
Scientific ReportsStrong mining tremors are a significant trigger of dynamic disasters in deep underground coal mines, especially within the near-field disturbance zone, where they induce intense dynamic disturbances and pronounced cyclic loading-unloading effects ...
Fan Chen +5 more
doaj +1 more source
High Temperature Materials and Processes, 2017 A series of uniaxial tensile tests were carried out at different strain rate and different temperatures to investigate the effects of temperature and strain rate on tensile deformation behavior of P92 steel.
Guo Xiaofeng +3 more
doaj +1 more source