Results 81 to 90 of about 27,396 (199)

Prevalence and Incidence of Diabetes‐Related Peripheral Neuropathy, Peripheral Artery Disease, Foot Ulcers and Lower Extremity Amputations in Ireland; A Systematic Review

Journal of Foot and Ankle Research, Volume 19, Issue 1, March 2026.
ABSTRACT Introduction Diabetes‐related foot disease is a leading cause of global disease burden, however the prevalence and incidence of diabetes‐related foot disease in Ireland is poorly understood. Up‐to‐date population‐level estimates of the incidence and prevalence are imperative to support appropriate health service planning.
Sinead Kavanagh, Jennifer A. Pallin, Ann Sinéad Doherty, Linda M. O'Keeffe, Steven Gilmore, Peter A. Lazzarini, Claire M. Buckley   +6 more
wiley   +1 more source

Sildenafil improves skeletal muscle oxygenation during exercise in men with intermittent claudication [PDF]

, 2014
Endothelial dysfunction caused by defective nitric oxide (NO) signaling plays a pivotal role in the pathogenesis of intermittent claudication (IC). in the present study, we evaluated the acute effects of sildenafil, a phosphodiesterase type 5 inhibitor ...
Alencar, Maria C., Hirai, Daniel M., Neder, J. Alberto, Nery, Luiz E., Ramos, Roberta P., Roseguini, Bruno T., Silva, Bruno M., Wolosker, Nelson   +7 more
core   +2 more sources

Exploring the Dynamics of Ischemia and Reactive Hyperemia With Skeletal Muscle Blood Oxygen Level Dependent MRI in Patients With Peripheral Artery Disease, Age‐Matched Controls, and Young Healthy Subjects

Journal of Magnetic Resonance Imaging, Volume 63, Issue 3, Page 813-825, March 2026.
ABSTRACT Background Skeletal muscle blood oxygen level dependent (BOLD) MRI is a technique for assessing vascular function in peripheral limbs. In patients, however, an increased frequency of atypical response patterns has been observed, warranting investigation into its underlying causes.
Jonathan Arvidsson, Stefanie Eriksson, Oscar Jalnefjord, Edvin Johansson, Joakim Nordanstig, Kerstin Lagerstrand   +5 more
wiley   +1 more source

Age disparities in SGLT2 inhibitor prescription among people with type 2 diabetes: The role of frailty and sex

Diabetes, Obesity and Metabolism, Volume 28, Issue 3, Page 2265-2276, March 2026.
Abstract Background Older adults with type 2 diabetes (T2DM) are less likely to receive sodium–glucose cotransporter‐2 (SGLT2) inhibitors, despite their proven cardio‐renal benefits and safety. Whether this age‐related gap is driven by frailty, sex, or other factors remains unclear.
Changyuan Yang, Petra Denig, Lynne Chepulis, Ryan G. Paul, Jung‐Im Shin, Ron T. Gansevoort, Priya Vart   +6 more
wiley   +1 more source

Racial Differences in the Effect of Granulocyte Macrophage Colony-Stimulating Factor on Improved Walking Distance in Peripheral Artery Disease: The PROPEL Randomized Clinical Trial. [PDF]

, 2019
Background The effects of race on response to medical therapy in people with peripheral artery disease ( PAD ) are unknown. Methods and Results In the PROPEL (Progenitor Cell Release Plus Exercise to Improve Functional Performance in PAD) Trial, PAD ...
Criqui, Michael H, Domanchuk, Kathryn, Ferrucci, Luigi, Guralnik, Jack M, Kibbe, Melina R, Li, Lingyu, McDermott, Mary M, Polonsky, Tamar S, Stein, James, Taylor, Doris A, Tian, Lu, Zhao, Lihui   +11 more
core   +1 more source

The prevalence of peripheral arterial disease in diabetic subjects in south-west Nigeria [PDF]

, 2012
Background: Peripheral arterial disease (PAD) is rarely sought for and generally underdiagnosed even in diabetics in developing countries like Nigeria.
Akintayo D. OlaOlorun, Bolaji O. Oyelade, Isaac O. Amole, Louis O. Odeigah, Olufemi S. Adediran   +4 more
core   +3 more sources

CYP2C19 genotype testing for clopidogrel: A guideline developed by the UK Centre of Excellence in Regulatory Science and Innovation in Pharmacogenomics (CERSI‐PGx)

British Journal of Clinical Pharmacology, Volume 92, Issue 2, Page 329-347, February 2026.
Clopidogrel, an antiplatelet agent, is currently licensed in the United Kingdom for the prevention and treatment of atherothrombotic events in cerebrovascular disease, coronary artery disease and peripheral arterial disease. Clopidogrel requires metabolic activation by the cytochrome P450 enzyme CYP2C19 to be effective.
Cinzia Dello Russo, Iain Frater, Rebecca Kuruvilla, Stefanie Lip, Hannah O'Neill, Kerry Burke, Vicky Chaplin, Alexander S. F. Doney, Salim Elyas, Nicholas Greaves, Sophie Harding, David Hargroves, Judith Hayward, Dyfrig A. Hughes, Tom A. T. Hughes, Sree Kondapally, Patrick Mok, Aaron Peace, Imran Rafi, Simon Ray, Vicky Stinton, Luigi Venetucci, Munir Pirmohamed   +22 more
wiley   +1 more source

Use of arteriography for the initial evaluation of patients with intermittent lower limb claudication

São Paulo Medical Journal
CONTEXT: Many patients with intermittent claudication continue to be forwarded to the vascular surgeon for initial evaluation after arteriography has already been accomplished.
Nelson Wolosker, Ruben Ayzin Rosoky, Kenji Nishinari, Lívio Nakano   +3 more
doaj   +1 more source

Heat Therapy: Targeting Health, Disease, and Disability

Comprehensive Physiology, Volume 16, Issue 1, February 2026.
The predominance of evidence suggests heat therapy has an impact on all aspects of health and performance, but the drivers of that improvement, the extent to which they are improved, and the specific populations in which improvements manifest are far from completely understood.
Rauchelle E. Richey, Robert D. Hyldahl, Brendan W. Kaiser, Paige C. Geiger, John R. Halliwill, Christopher T. Minson   +5 more
wiley   +1 more source

A Case of Polyarteritis Nodosa Presenting as Rapidly Progressing Intermittent Claudication of Right Leg

Case Reports in Medicine, 2017
Background. Polyarteritis nodosa (PAN) is a medium vessel vasculitis which causes significant morbidity and mortality. Usually, it presents with constitutional symptoms with angiographic evidence of aneurysms or segmental stenosis of arteries of ...
Chathuranga Lakmal Fonseka, Sampath Rukshani Galappaththi, Dayakshi Abeyaratne, Nirmali Tissera, Lalith Wijayaratne   +4 more
doaj   +1 more source