Results 181 to 190 of about 32,360 (254)

What Works in Type 2 Diabetes: Intermittent Fasting or Calorie Restriction or Both? [PDF]

Indian J Endocrinol Metab
Nagendra L, Bhattacharya S, Kapoor N, Kalra S.   +3 more
europepmc   +1 more source

Discovery and Optimization of AMT‐676, a CDH17‐Targeting ADC for the Treatment of Advanced Gastrointestinal Cancers

Advanced Science, EarlyView.
AMT‐676 is a novel antibody‐drug conjugate targeting CDH17, an adhesion molecule uniquely exposed on gastrointestinal tumor surfaces. Engineered with an optimized exatecan payload, it demonstrates profound tumor regression and a robust bystander effect across diverse preclinical models.
Ying‐nan Wang, Dan‐yun Ruan, Jing Shi, Yue Huang, Hui Sheng, Ya‐ling Huang, Linjie Ma, Lijun Wang, Caiwei Chen, Yixuan Wang, Yue Zhang, Yi Shen, Qing Zhang, Jianjian Zhang, Yanfang Tang, Jin‐ling Zhang, Jia‐jia Hu, Chen‐yi Wu, Jia‐ying Chen, Xun Meng, Shu‐Hui Liu, Feng Wang   +21 more
wiley   +1 more source

Correction to "Body Weight Changes During Ramadan Intermittent Fasting: A Cross-Sectional Study of Healthy Adults in Turkey". [PDF]

J Nutr Metab
europepmc   +1 more source

TECTB Variants Reveal Tectorial Membrane Vulnerability in Dominant Non‐Syndromic Hearing Loss

Advanced Science, EarlyView.
TECTB is a non‐collagenous protein of the tectorial membrane – an extracellular matrix of the cochlea. This study identifies dominant missense variants in TECTB linked to human hereditary deafness in two unrelated families. Genetically engineered mice homozygous for one of the variants are profoundly deaf, whereas heterozygous mice have normal hearing ...
Evan B. Hale, Barbara Vona, Richard J. Goodyear, Richard T. Osgood, Jun Shen, Sami S. Amr, Karen Mojica, Michaela A. H. Hofrichter, Jörg Schröder, Sophie Flandin, Paul Gratias, Ricardo Vera‐Monroy, Katherine Callahan, Kerry L. Gudlewski, Rolen Quadros, Masato Ohtsuka, JoAnn McGee, Edward J. Walsh, Cynthia C. Morton, Thomas Haaf, Channabasavaiah Gurumurthy, James E. Saunders, Guy P. Richardson, Artur A. Indzhykulian   +23 more
wiley   +1 more source

Longitudinal changes in intracortical excitability during Ramadan diurnal intermittent fasting: A paired-pulse transcranial magnetic stimulation study. [PDF]

PLoS One
Kim M, Mostafa IM, Al-Sharman A, Saad N, Khalil H, Hadoush H.   +5 more
europepmc   +1 more source

Elastomeric Core‐Conductive Shell Slurry Additive Stabilizes High‐Voltage NCM811 Cathodes via Mechanical‐Electrical Dual Regulation

Advanced Science, EarlyView.
A core‐shell ASA slurry additive constructs a mosaic‐like interface on high‐voltage NCM811 cathodes. This architecture decouples interfacial functions: the elastomeric core buffers mechanical stress to prevent microcracking, while the conductive shell facilitates rapid ion/electron transport, enabling mechanical‐electrical dual regulation and enhanced ...
Jiamin Duan, Xingchen Liu, Jiapei Li, Zhuijun Xu, Said Amzil, Baohu Wu, Yiyao Xiao, Wenjun Zhang, Tong Yu, Xiaohong Li, Wenwen Xue, Xiangyu Chen, Changwei Liu, Jie Gao, Peter Müller‐Buschbaum, Ya‐Jun Cheng, Yonggao Xia   +16 more
wiley   +1 more source

Intermittent Fasting: A Metabolically Focused Therapeutic Strategy for Obesity. [PDF]

Nutrients
Diaz-Garrido N, Zagmutt S, Regaldiz A, Cisternas P, Bastías-Pérez M.   +4 more
europepmc   +1 more source

Probabilistic Computing via Gate‐Tunable Random Telegraph Noise

Advanced Science, EarlyView.
Intrinsic random telegraph noise in metal–oxide–semiconductor field‐effect transistors is harnessed to create gate‐tunable probabilistic bits. By modulating carrier‐trapping dynamics, the device produces stochastic binary outputs with a continuous bias‐to‐probability transfer.
Gyungwon Yun, Jin Pyo Kang, Ho‐Sung Lee, Ik‐Hyeon Jeon, Ki‐Ju Park, Won‐Ju Cho, Seung‐heon Chris Baek, Joo‐Hyung Chae, Hamin Park   +8 more
wiley   +1 more source

Intermittent Fasting and Fat-Free Mass Outcomes in Middle-Aged and Older Adults: A Scoping Review. [PDF]

Adv Nutr
Santero S, Blagojević BD, Merzah M, Celada Guerrero JA, Cena H, Ordovas JM, Ruiz LD.   +6 more
europepmc   +1 more source

Weakly Coordinated Solvent Network‐Induced Ternary Water‐Deficient Eutectic Electrolytes for Low‐Polarization Zn Anodes

Advanced Science, EarlyView.
A water‐deficient ternary eutectic electrolyte employs weakly coordinating solvents to decouple strong solvation interactions, constructing a loose and dynamic solvation network. This optimized solvation structure accelerates Zn2+ transport and interfacial kinetics, promotes robust SEI formation, and ultimately enables highly stable and reversible Zn ...
Quancai Li, Jing Liang, Jiayu Wang, Qian Wang, Hehe Ren, Ziyi Gong, Vellaisamy A. L. Roy, Wei Wu   +7 more
wiley   +1 more source