Extended infusion versus intermittent infusion of imipenem in the treatment of ventilator-associated pneumonia [PDF]
Drug Design, Development and Therapy, 2017 Mohamed M Ibrahim,1 Tarek Fouad Tammam,2 Mohy El Deen Ebaed,3 Hatem A Sarhan,4 Gamal F Gad,5 Amal K Hussein4 1Department of Clinical Pharmacy, Faculty of Pharmacy, Minia University, Minia, Egypt; 2Department of Anesthesia and Intensive Care, Faculty of ...
Ibrahim MM +5 more
doaj +7 more sources
Cefepime extended infusion versus intermittent infusion: Clinical and cost evaluation [PDF]
Antimicrobial Stewardship & Healthcare Epidemiology, 2023 Background: Extended infusion cefepime (1 gram every 6 hours administered over 3 hours) achieves pharmacodynamic efficacy against bacteria with a MIC of ≤8 mg/L in Monte Carlo simulations.
Aalok V. Khole +3 more
doaj +5 more sources
Continuous Vancomycin Infusion versus Intermittent Infusion in Critically Ill Patients [PDF]
Infection and Drug Resistance, 2022 Chailat Maluangnon, Surat Tongyoo, Chairat Permpikul Department of Medicine, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, ThailandCorrespondence: Chairat Permpikul, Department of Medicine, Faculty of Medicine, Siriraj Hospital ...
Maluangnon C, Tongyoo S, Permpikul C
doaj +4 more sources
Pharmaceuticals, 2022 High variability of linezolid blood concentrations with partial subtherapeutic levels was observed in critically ill patients who received a standard intravenous dose of linezolid, contributing to drug resistance and toxicity.
Heba Salem, Ayman Moharram
exaly +4 more sources
Extended infusion of piperacillin–tazobactam versus intermittent infusion in critically ill egyptian patients: a cost-effectiveness study [PDF]
Scientific Reports, 2022 Extended infusion of piperacillin/tazobactam over 4 h has been proposed as an alternate mode of administration to the 30-min intermittent infusion to optimize treatment effects in patients with gram-negative bacterial infections.
Christina Medhat Naiim +3 more
doaj +2 more sources
Comparison of the Effectiveness of Prolonged Infusion and Intermittent Infusion of Meropenem in Patients With Sepsis: A Meta-Analysis. [PDF]
Cureus, 2023 The aim of this study was to compare the clinical effectiveness of prolonged infusion and intermittent infusion of meropenem in patients with sepsis. This meta-analysis was conducted following the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) 2020 guidelines.
Lokhandwala A +7 more
europepmc +3 more sources
Comparison of bispectral index-guided endoscopic ultrasonography with continuous versus intermittent infusion of propofol: a retrospective study in Japan [PDF]
Clinical EndoscopyBackground/Aims This study aimed to evaluate the safety and efficacy of continuous propofol infusion for anesthesia during endoscopic ultrasonography (EUS).
Ayana Okamoto +6 more
doaj +2 more sources
Continuous versus intermittent infusion of β-lactams in patients with sepsis and septic shock: a systematic review and meta-analysis [PDF]
BMC Infectious DiseasesObjective To assess whether continuous infusion of β-lactam antibiotics improves clinical outcomes compared to intermittent infusion in adult patients with sepsis or septic shock.
David A. Tejada +5 more
doaj +2 more sources
Antibiotics, 2022 A judicious antibiotic therapy is one of the challenges in the therapy of critically ill patients with sepsis and septic shock. The pathophysiological changes in these patients significantly alter the antibiotic pharmacokinetics (PK) and pharmacodynamics
Laurian Vlase +2 more
exaly +3 more sources
Linezolid Pharmacokinetics in Critically Ill Patients: Continuous Versus Intermittent Infusion [PDF]
AntibioticsBackground: Linezolid has been found to have considerable interindividual variability, especially in critically ill patients, which can lead to suboptimal plasma concentration. To overcome this shortcoming, several solutions have been proposed.
Ligia-Ancuța Hui +5 more
doaj +2 more sources