Results 81 to 90 of about 376,440 (283)

A Magneto‐Mechanically Activated Nerve Guidance Conduit Promotes Peripheral Nerve Regeneration via TIMP1‐Mediated Membrane Tension Transfer

Advanced Functional Materials, EarlyView.
This study presents a magneto‐mechanical strategy that incorporates FP@MSCs into an aligned PCL/GelMA nerve guidance conduit. Magnetic stimulation increases membrane tension in FP@MSCs, triggering cytoskeletal remodeling, Schwann cell‐like differentiation, and TIMP1 secretion. TIMP1 activates ITGB1/CD63–FAK signaling in NE‐4C cells, increasing membrane
Xinyu Zhu, Yumin Wu, Xiang Gao, Tianlu Wang, Wanting Jia, Xueying Mei, Huanzhong Ji, Zongxi Wu, Yujie Liang, Xiang Li, Kan Li, Jingyuan Li, Guangsen Zheng, Guiqing Liao, Siyong Gao   +14 more
wiley   +1 more source

Continuous versus intermittent bolus infusion of calcium in preterm infants receiving total parenteral nutrition: a randomized blind clinical trial

BMC Pediatrics
Background Premature neonates need adequate nutritional support to provide sufficient essential nutrients for optimal growth. Calcium (Ca) is one of the important nutrients in parental nutrition support of premature infants.
Siamak Shiva, Khatereh Rezazadeh, Asmar Amiraslanzadeh, Bahareh Mehramuz, Sadollah Yeganehdoost, Majid Mahallei   +5 more
doaj   +1 more source

Evaluation Outcomes Associated with Alternative Dosing Strategies for Piperacillin/Tazobactam: A Systematic Review and Meta-Analysis

Journal of Pharmacy & Pharmaceutical Sciences, 2016
A better dosing strategy can improve clinical outcomes for patients. We systematically reviewed the literatures to determine whether any clinical benefits exist for piperacillin/tazobactam by extended or continuous infusion. Methods - A search of PubMed,
Hui Yang, Xiangli Cui, Zhuo Ma, Lihong Liu   +3 more
doaj   +1 more source

Influences of intermittent preventive treatment and persistent multiclonal Plasmodium falciparum infections on clinical malaria risk. [PDF]

, 2010
BACKGROUND: Intermittent preventive treatment (IPT) of malaria involves administration of curative doses of antimalarials at specified time points to vulnerable populations in endemic areas, regardless whether a subject is known to be infected.
Färnert, Anna, Kweku Margaret, Olsson Daniel, Daniel Olsson, Kweku, Margaret,, Daniel Chandramohan, Margaret Kweku, Chandramohan, Daniel,, Montgomery, Scott M.,, Montgomery, Scott M, Scott M. Montgomery, Liljander Anne, Liljander, Anne,, Greenwood, Brian,, Greenwood, Brian, Brian Greenwood, Kweku, Margaret, Chandramohan Daniel, Montgomery Scott M., Olsson, Daniel,, Greenwood Brian, Anna Färnert, Färnert, Anna,, Chandramohan, Daniel, Scott M Montgomery, Liljander, Anne, Anne Liljander, Färnert Anna, Olsson, Daniel, Kweku, M, Farnert, A, Liljander, A, Greenwood, B, Chandramohan, D, Olsson, D,, Montgomery, SM   +35 more
core   +2 more sources

Targeting CD300a Signaling With a Phosphatidylserine‐Presenting Hydrogel Rescues Macrophage Dysfunction and Accelerates Diabetic Wound Healing

Advanced Healthcare Materials, EarlyView.
Schematic illustration of the proposed mechanism: PEG/RGD‐PSLs mimic apoptotic cells to engage PS receptors (notably CD300a), transducing an inhibitory signal that suppresses the MyD88/NF‐κB pathway, leading to global anti‐inflammatory and pro‐reparative effects.
Lele Wu, Xuetong Hao, Yang Zou, Xinglin Chen, Junyan Kong, Chunning Gu, Wenjie Ma, Zhongjun Yang, Huifen Liu, Mengmeng Liu, Xin Tong   +10 more
wiley   +1 more source

A Geometrically Transient Platform for Bioelectronic Implants

Advanced Materials, EarlyView.
Minimally invasive bioelectronic implants often compromise performance for smaller sizes. To resolve this optimization dilemma, a wireless bioelectronic implant with a transient geometry is introduced (MiFi). The origami‐inspired device miniaturizes up to sixfold for syringe insertion and autonomously unfolds post‐implantation.
Selin Olenik, John D. Goodwin, Atharv Naik, Philip Coatsworth, Ioi Chit Cheung, Farbod Amirghasemi, Anies Sohi, Ehsan Abedi, Tayeb Tadlaoui, Maral P. S. Mousavi, Andriy S. Kozlov, Victoria Salem, Andrew S. Cowburn, Firat Guder   +13 more
wiley   +1 more source

Enteral nutrition in critical patients: should the administration be continuous or intermittent?

Nutrición Hospitalaria, 2014
Enteral nutrition therapy (ENT) is an essential part in the management of critically ill patients, having a significant impact on these patients´ clinical results. It can be administered on a continuous or intermittent basis using an infusion pump. There
Viviane Maeve Tavares de Araujo, Paulo César Gomes, Cervantes Caporossi   +2 more
doaj   +1 more source

Extended infusion versus intermittent infusion of Piperacillin/tazobactam: altering current methods to optimize future outcome

, 2023
Due to worldwide bacterial resistance, researchers and clinicians were required to optimize existing antimicrobials by influencing the pharmacokinetics and pharmacodynamics (PK/PD) features. Piperacillin/tazobactam (PIP/TZB) is one of the most frequently
Mohammed AlShehail, Bashayer, Alenazi, Ahmed, Alhamed, Nada, Alsultan, Mohammed M., Alabdullatif, Ammar, Aldhafeeri, Maha, Al Jamea, Zainab   +6 more
core  

Electrolyte Design for Fast‐Charging Lithium‐Based Batteries

Advanced Materials, EarlyView.
A decade of progress in fast‐charging electrolytes for lithium batteries is reviewed. Electrolyte design strategies spanning solvents, salts, additives, and advanced systems, such as localized high‐concentration electrolytes (LHCEs), are summarized. Advanced diagnostic tools for lithium plating and interphase chemistry are discussed, with perspectives ...
Chen Liu, Zehao Cui, Arumugam Manthiram
wiley   +1 more source

Prolonged versus intermittent β-lactam infusion in sepsis: a systematic review and meta-analysis of randomized controlled trials

Annals of Intensive Care
Background The two latest studies on prolonged versus intermittent use of β-lactam antibiotics in patients with sepsis did not reach consistent conclusions, further contributing to the controversy surrounding the effectiveness of the prolonged β-lactam ...
Yang Zhao, Bin Zang, Qian Wang
doaj   +1 more source